Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Objective Early-onset colorectal cancer (CRC) is increasing in the USA despite rapid
declines in older ages. Similar patterns are reported in Australia and Canada, but a …

Background The overall incidence of colorectal cancer is decreasing in many high-income
countries, yet analyses in the USA and other high-income countries such as Australia …

In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the
incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in …

Background & Aims Early-onset colorectal cancer (CRC, in persons younger than 50 years
old) is increasing in incidence; yet, in the absence of a family history of CRC, this population …

Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting
broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are …

Many cancer referral guidelines use patient's age as a key criterium to decide who should
be referred urgently. A recent rise in the incidence of colorectal cancer in younger adults has …

Background The incidence of colorectal cancer (CRC) among individuals aged younger
than 50 years has been increasing. As screening guidelines lower the recommended age of …