This article reviews synthetic transformations involving cleavage of a carbon–carbon bond of
a four-membered ring, with a particular focus on the examples reported during the period …

Transition-metal-catalyzed activation of C–H and C–C bonds is a challenging area in
synthetic organic chemistry. Among various methods to accomplish these processes, the …

The C− N bond is one of the most abundant chemical bonds and widely exists in many
organic molecules and biomacromolecules. The formation and transformation of C− N …

Exploiting the reactivity of one functional group within a molecule to generate a reaction at a
different position is an ongoing challenge in organic synthesis. Effective remote …

The functionalization of molecules by cleaving inert carbon–carbon single bonds is
regarded as a great synthetic challenge due to their inherent stability. In recent years …

Recent developments in the stereoselective synthesis of polysubstituted cyclopropanes
nowadays allow chemists to easily access these strained rings with high diastereo-and …

The transition-metal-catalyzed “cut and sew” transformation has recently emerged as a
useful strategy for preparing complex molecular structures. After oxidative addition of a …

The cleavage of C–C bonds has been a great challenge owing to their thermodynamic and
kinetic stability. To date, the progress made in this area has mainly relied on the reaction of …

Organosilicon compounds act as a nucleophile upon activation by an appropriate base and
behave in a manner similar to main-group organometallic reagents. In the last decades …

The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …