Low intensity focused ultrasound for epilepsy—A new approach to neuromodulation

EJ Bubrick, NJ McDannold, PJ White - Epilepsy Currents, 2022 - journals.sagepub.com
Patients with drug-resistant epilepsy (DRE) who are not surgical candidates have
unacceptably few treatment options. Benefits of implanted electrostimulatory devices are still …

Translational approaches to influence sleep and arousal

RE Brown, TJ Spratt, GB Kaplan - Brain research bulletin, 2022 - Elsevier
Sleep disorders are widespread in society and are prevalent in military personnel and in
Veterans. Disturbances of sleep and arousal mechanisms are common in neuropsychiatric …

Transcranial focused ultrasound stimulation of cortical and thalamic somatosensory areas in human

HC Kim, W Lee, DS Weisholtz, SS Yoo - PLoS One, 2023 - journals.plos.org
The effects of transcranial focused ultrasound (FUS) stimulation of the primary
somatosensory cortex and its thalamic projection (ie, ventral posterolateral nucleus) on the …

Non-invasive enhancement of intracortical solute clearance using transcranial focused ultrasound

SS Yoo, E Kim, K Kowsari, J Van Reet, HC Kim… - Scientific reports, 2023 - nature.com
Transport of interstitial fluid and solutes plays a critical role in clearing metabolic waste from
the brain. Transcranial application of focused ultrasound (FUS) has been shown to promote …

Weak ultrasound contributes to neuromodulatory effects in the rat motor cortex

PC Chu, CS Huang, PK Chang, RS Chen… - International Journal of …, 2023 - mdpi.com
Transcranial focused ultrasound (tFUS) is a novel neuromodulating technique. It has been
demonstrated that the neuromodulatory effects can be induced by weak ultrasound …

Enhancement of cerebrospinal fluid tracer movement by the application of pulsed transcranial focused ultrasound

SS Yoo, HC Kim, J Kim, E Kim, K Kowsari, J Van Reet… - Scientific reports, 2022 - nature.com
Efficient transport of solutes in the cerebrospinal fluid (CSF) plays a critical role in their
clearance from the brain. Convective bulk flow of solutes in the CSF in the perivascular …

Effects of focused ultrasound pulse duration on stimulating cortical and subcortical motor circuits in awake sheep

HC Kim, W Lee, K Kowsari, DS Weisholtz, SS Yoo - PLoS One, 2022 - journals.plos.org
Low-intensity transcranial focused ultrasound (tFUS) offers new functional neuromodulation
opportunities, enabling stimulation of cortical as well as deep brain areas with high spatial …

Transcranial ultrasound neuromodulation induces neuronal correlation change in the rat somatosensory cortex

S Ramachandran, X Niu, K Yu… - Journal of neural …, 2022 - iopscience.iop.org
Objective. Transcranial focused ultrasound (tFUS) is a neuromodulation technique which
has been the focus of increasing interest for noninvasive brain stimulation with high spatial …

Modulation effect of low-intensity transcranial ultrasound stimulation on REM and NREM sleep

T Wang, X Wang, Y Tian, W Gang, X Li, J Yan… - Cerebral …, 2023 - academic.oup.com
Previous studies have shown that modulating neural activity can affect rapid eye movement
(REM) and non-rapid eye movement (NREM) sleep. Low-intensity transcranial ultrasound …

Low-intensity focused ultrasound neuromodulation for stroke recovery: A novel deep brain stimulation approach for neurorehabilitation?

MM Yüksel, S Sun, C Latchoumane… - IEEE Open Journal …, 2023 - ieeexplore.ieee.org
Stroke as the leading cause of adult long-term disability and has a significant impact on
patients, society and socio-economics. Non-invasive brain stimulation (NIBS) approaches …