Updates on malaria epidemiology and prevention strategies

M González-Sanz, P Berzosa, FF Norman - Current Infectious Disease …, 2023 - Springer
Abstract Purpose of Review The objective of this review was to provide an update on recent
malaria epidemiology, both globally and in non-endemic areas, to identify the current …

Systematic review of the status of pfhrp2 and pfhrp3 gene deletion, approaches and methods used for its estimation and reporting in Plasmodium falciparum …

BB Agaba, A Yeka, S Nsobya, E Arinaitwe… - Malaria journal, 2019 - Springer
Background Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a
vital role in improving malaria case management and surveillance particularly in Africa …

Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria

RA Lee, HD Puig, PQ Nguyen… - Proceedings of the …, 2020 - National Acad Sciences
Asymptomatic carriers of Plasmodium parasites hamper malaria control and eradication.
Achieving malaria eradication requires ultrasensitive diagnostics for low parasite density …

Genetic diversity and deletion of Plasmodium falciparum histidine-rich protein 2 and 3: a threat to diagnosis of P. falciparum malaria

M Gendrot, R Fawaz, J Dormoi, M Madamet… - Clinical Microbiology …, 2019 - Elsevier
Background PfHRP2-based rapid diagnostic tests (RDTs), based on the recognition of the
Plasmodium falciparum histidine-rich protein 2, are currently the most used tests in malaria …

Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosis

GS Alemayehu, K Blackburn, K Lopez… - Malaria journal, 2021 - Springer
Abstract Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2 (HRP2)
are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the …

False-negative malaria rapid diagnostic test results and their impact on community-based malaria surveys in sub-Saharan Africa

OJ Watson, KM Sumner, M Janko, V Goel, P Winskill… - BMJ global …, 2019 - gh.bmj.com
Surveillance and diagnosis of Plasmodium falciparum malaria relies predominantly on rapid
diagnostic tests (RDT). However, false-negative (FN) RDT results are known to occur for a …

Plasmodium falciparum histidine-rich protein 2 and 3 genes deletion in global settings (2010–2021): a systematic review and meta-analysis

A Jejaw Zeleke, A Hailu, AG Bayih, M Kefale, AT Amare… - Malaria Journal, 2022 - Springer
Background The usefulness of histidine-rich protein-2/3 (HRP2/3)-based rapid diagnostic
tests of malaria due to Plasmodium falciparum has been threatened by the appearance of …

First evidence of the deletion in the pfhrp2 and pfhrp3 genes in Plasmodium falciparum from Equatorial Guinea

P Berzosa, V González, L Taravillo, A Mayor… - Malaria journal, 2020 - Springer
Abstract Background The World Health Organization (WHO) recommends rapid diagnostic
tests (RDTs) as a good alternative malaria-diagnosis method in remote parts of sub-Saharan …

Impact of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions on malaria control worldwide: a systematic review and meta-analysis

I Molina-de la Fuente, A Pastor, Z Herrador, A Benito… - Malaria journal, 2021 - Springer
Background Deletion of pfhrp2 and/or pfhrp3 genes cause false negatives in malaria rapid
diagnostic test (RDT) and threating malaria control strategies. This systematic review aims to …

Harnessing the potential of miRNAs in malaria diagnostic and prevention

H Gupta, SC Wassmer - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Despite encouraging progress over the past decade, malaria remains a major global health
challenge. Its severe form accounts for the majority of malaria-related deaths, and early …