Integrating mathematical modeling into the roadmap for personalized adaptive radiation therapy

H Enderling, JCL Alfonso, E Moros, JJ Caudell… - Trends in cancer, 2019 - cell.com
In current radiation oncology practice, treatment protocols are prescribed based on the
average outcomes of large clinical trials, with limited personalization and without …

The challenge of early detection in cancer

N Pashayan, PDP Pharoah - Science, 2020 - science.org
The chances of survival for a patient with cancer are substantially improved if the disease is
diagnosed and treated at an early clinical stage (1). This underpins the promise of early …

From colitis to cancer: an evolutionary trajectory that merges maths and biology

I Al Bakir, K Curtius, TA Graham - Frontiers in immunology, 2018 - frontiersin.org
Patients with inflammatory bowel disease have an increased risk of developing colorectal
cancer, and this risk is related to disease duration, extent, and cumulative inflammation …

Proliferation saturation index in an adaptive Bayesian approach to predict patient-specific radiotherapy responses

ED Sunassee, D Tan, N Ji, R Brady… - … journal of radiation …, 2019 - Taylor & Francis
Purpose: Radiotherapy prescription dose and dose fractionation protocols vary little
between individual patients having the same tumor grade and stage. To personalize …

Predicting the effectiveness of chemotherapy using stochastic ODE models of tumor growth

S Sharpe, HM Dobrovolny - Communications in Nonlinear Science and …, 2021 - Elsevier
Ordinary differential equation (ODE) models of cancer growth are often used to predict tumor
growth and form the basis for more complex models used in personalized medicine …

CD133 expression as a helicobacter pylori-independent biomarker of gastric cancer progression

R Howard, S Al Diffalha, J Pimiento, J Mejia… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Gastric adenocarcinoma is the fourth most common cancer worldwide.
While gastric cancer prevalence varies globally and incidence rates are decreasing in the …

[HTML][HTML] The role of “Prominin–1” marker in adenomatous colorectal polyps

A Safiyeva, N Bayramov, M Avunduk - Polish Journal of Surgery, 2021 - ppch.pl
Introduction: Adenomatous polyps are pivotal to the development of colorectal cancer. The
risk of colorectal carcinogenesis can be reduced through polypectomy and close …

The Prognostic Importance of Cancer Stem Cells in Colorectal Polyps

A Safiyeva, N Bayramov… - Annali Italiani di …, 2024 - annaliitalianidichirurgia.it
Background: This purpose aims to investigate the usefulness of CD133, a stem cell marker,
for the prognosis of colon polyps. This study aimed to assess the adenomatous polyps that …

High School Internship Program in Integrated Mathematical Oncology (HIP IMO): Five-Year Experience at Moffitt Cancer Center

H Enderling, PM Altrock, N Andor, D Basanta… - Bulletin of Mathematical …, 2020 - Springer
Modern cancer research, and the wealth of data across multiple spatial and temporal scales,
has created the need for researchers that are well versed in the life sciences (cancer …

[HTML][HTML] Immunohistochemical analysis of LGR5 and TROY expression in gastric carcinogenesis demonstrates an inverse trend

S Saberi, A Piryaei, E Mirabzadeh… - Iranian Biomedical …, 2019 - ncbi.nlm.nih.gov
Background: Two of the Wnt signaling pathway target genes, tumor necrosis factor receptor
family member (TROY) and leucine-rich G-protein coupled receptor (LGR5), are involved in …