Despite advances in antimicrobial and anti-inflammatory therapies, inflammation and its
consequences still remain a significant problem in medicine. Acute inflammatory responses …

Parkinson's Disease (PD) is the second most common neurodegenerative disorder seen,
especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance …

Mitochondrial dysfunction and the loss of mitophagy, aimed at recycling irreversibly
damaged organelles, contribute to the onset of amyotrophic lateral sclerosis (ALS), a fatal …

Abstract Background Neural stem cells (NSCs) have the ability to generate a variety of
functional neural cell types and have a high potential for neuronal cell regeneration and …

Our understanding of the role of innate and adaptive immune cell function in brain health
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …

Objective To assess the presence of brain and systemic inflammation in subjects newly
diagnosed with Parkinson's disease (PD). Background Evidence for a pathophysiologic role …

Background Abnormal activation of immune system is an important pathogenesis of
Parkinson's disease, but the relationship between peripheral inflammation, central microglia …

Background and Objectives Recent imaging studies have suggested a possible involvement
of the choroid plexus (CP) in multiple sclerosis (MS). Here, we investigated whether CP …

Neuroinflammation plays a major role in the etiopathology of neurodegenerative diseases,
including Alzheimer and Parkinson diseases, frontotemporal lobar degeneration, and …

Microglia are the primary resident immune cells of the central nervous system.
Neuropathological reports have identified augmented microglial activation in brains of …