Cystic fibrosis is a genetic disease with multisystem involvement and associated morbidity
and mortality that are most directly related to progressive lung disease. The hallmark …

Objective Imaging represents an important noninvasive means to assess cystic fibrosis (CF)
lung disease, which remains the main cause of morbidity and mortality in CF patients. While …

Rationale: Clinical trials have shown that use of elexacaftor/tezacaftor/ivacaftor (ETI) is
associated with improvements in sweat chloride, pulmonary function, nutrition, and quality of …

Background Lung MRI with ultrashort echo times (UTEs) enables high-resolution and
radiation-free morphologic imaging; however, its image quality is still lower than that of CT …

BACKGROUND Information about the size, airway location, and longitudinal behavior of
mucus plugs in asthma is needed to understand their role in mechanisms of airflow …

Background: Newly developed quantitative chest computed tomography (CT) outcomes
designed specifically to assess structural abnormalities related to cystic fibrosis (CF) lung …

Objectives Holistic segmentation of CT structural alterations with 3D deep learning has
recently been described in cystic fibrosis (CF), allowing the measurement of normalized …

Bronchiectasis (BE) is a chronic condition characterized by airway dilation as a
consequence of a variety of pathogenic processes. It is often associated with persistent …

Imaging plays a pivotal role in the noninvasive assessment of cystic fibrosis (CF)-related
lung damage, which remains the main cause of morbidity and mortality in children with CF …

Introduction: The availability of highly effective triple cystic fibrosis transmembrane
conductance regulator (CFTR) modulator combination therapy with elexacaftor–tezacaftor …