The disruption of balance between production of reactive oxygen species and antioxidant
systems in favor of the oxidants is termed oxidative stress (OS). To counteract the damaging …

Toxins are natural or chemical poisonous substances with severe side effects on health.
Humans are generally exposed by widespread toxic contaminations via air, soil, water, food …

Nephrotoxicity is one of the limiting factors for using doxorubicin (Dox) as an anticancer
chemotherapeutic. Here, we investigated possible protective effect of coenzyme‐Q10 …

Gentamicin (GM) is an effective aminoglycoside antibiotic against severe infections but
nephrotoxicity and oxidative damage limits its long term clinical use. Various strategies were …

The potential protective effect of coenzyme Q10 against acute liver injury induced by a
single dose of acetaminophen (700mg/kg, po) was investigated in rats. Coenzyme Q10 …

Ginsenoside Rb2 (Rb2), a fundamental saponin produced and isolated from ginseng
(Panax ginseng CA Meyer), has a wide range of biological actions. The objective of this …

This review describes recent advances in our understanding of the uptake and distribution of
coenzyme Q10 (CoQ10) in cells, animals, and humans. These advances have provided …

Benzoquinones are class of natural quinones found chiefly in higher plants, fungi, bacteria
and animal kingdom. They are involved in important biological functions such as …

Cisplatin (CP) an anticancer drug is known to induce nephrotoxicity, which limits its long-
term clinical use. Green tea (GT), consumed since ancient times is known for its numerous …

Recent studies indicate that free radicals are important mediators of renal damage induced
by gentamicin (GM), an aminoglycoside antibiotic widely used in treating severe gram …