Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …

The zona pellucida (ZP) is an extracellular matrix that surrounds all mammalian oocytes,
eggs, and early embryos and plays vital roles during oogenesis, fertilization, and …

Transition of soluble proteins into insoluble amyloid fibrils is driven by self-propagating short
sequence stretches. However, accurate prediction of aggregation determinants remains …

The human zona pellucida (ZP) is an extracellular glycoprotein matrix composed of ZP1,
ZP2, ZP3, and ZP4 surrounding the oocyte, and it plays an important role in sperm–egg …

It is still unclear why pathological amyloid deposition initiates in specific brain regions or why
some cells or tissues are more susceptible than others. Amyloid deposition is determined by …

With the development of nanotechnology, functional amyloid materials are drawing
increasing attention, and numerous remarkable applications are emerging. Amyloids …

Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP
glycoprotein-1 (ZP1),-2 (ZP2),-3 (ZP3), and-4 (ZP4). Mutations in the genes encoding human …

Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

Amyloids cause incurable diseases in humans and animals and regulate vital processes in
bacteria and eukaryotes. Amyloid fibrils have unique properties, such as amazing resistance …

Active accumulation of the data on new amyloids continuing nowadays dissolves
boundaries of the term “amyloid”. Currently, it is most often used to designate aggregates …