Impact of sex and gender on axSpA diagnosis and outcomes

SO Kohn, A Azam, LE Hamilton, SR Harrison… - Best Practice & …, 2023 - Elsevier
Axial spondyloarthritis (axSpA) was historically considered a disease of men, largely due to
the recognition of a more severe, progressive phenotype, ankylosing spondylitis (AS; or …

Comparative efficacy and safety of bimekizumab in axial spondyloarthritis: a systematic literature review and network meta-analysis

A Deodhar, PM Machado, M Mørup, V Taieb… - …, 2024 - academic.oup.com
Objectives To compare the efficacy and safety of bimekizumab 160 mg every 4 weeks, a
selective inhibitor of IL-17F and IL-17A, with those of biologic/targeted synthetic DMARDs …

Unmet needs in axial spondyloarthritis. Proceedings of the French spondyloarthritis taskforce workshop

D Wendling, M Breban, F Costantino, T Lequerré… - Joint Bone Spine, 2024 - Elsevier
The progress observed over the last 30 years in the field of axial spondyloarthritis (axSpA)
has not made it possible to answer all the current questions. This manuscript represents the …

Sex differences in patient-reported outcome measures and the association with clinical factors in axial spondyloarthritis patients treated with tumour necrosis factor …

P Hellamand, MGH Van de Sande… - …, 2024 - academic.oup.com
Objectives To investigate sex differences in patient-reported outcome measures (PROMs)
among axSpA patients initiating their first TNFi and identify factors contributing to these …

[HTML][HTML] Performance of cut-offs of the ASAS Health Index to discriminate between treatment groups in patients with axial spondyloarthritis in the TICOSPA trial

U Kiltz, A Molto, C Lopez-Medina, M Dougados… - Seminars in Arthritis and …, 2024 - Elsevier
Objective To test trial and longitudinal known group discrimination of thresholds of meaning
for improvement and health states of the ASAS Health Index (ASAS HI) in patients with …

The management of axial spondyloarthritis with cutting-edge therapies: advancements and innovations

G Lopalco, A Cito, V Venerito, F Iannone… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Axial involvement in spondyloarthritis has significantly evolved from the original
1984 New York criteria for ankylosing spondylitis, leading to an improved understanding of …

The failure of biological treatment in axial spondyloarthritis is linked to the factors related to increased intestinal permeability and dysbiosis: prospective observational …

M Chmielińska, A Felis-Giemza, M Olesińska… - Rheumatology …, 2024 - Springer
Background A significant number of patients with axial spondyloarthritis (axSpA) do not
respond to biological therapy. Therefore, we decided to investigate the specificity of this …

Impact of patient characteristics on ASDAS disease activity state cut-offs in axial spondyloarthritis: results from nine European rheumatology registries

LM Ørnbjerg, S Georgiadis, TK Kvien, B Michelsen… - RMD open, 2024 - rmdopen.bmj.com
Objectives To re-evaluate cut-offs for disease activity states according to the Axial
Spondyloarthritis Disease Activity Score (ASDAS), and study the impact of sex, age …

Patient-tailored dose reduction of tumor necrosis factor inhibitors in axial spondyloarthritis

JX Huang, YH Lee, JCC Wei - International Immunopharmacology, 2023 - Elsevier
Tumor necrosis factor inhibitors have been widely used in the field of axial spondyloarthritis,
with current guidelines now recommending dose reduction instead of withdrawal of …

Early clinical response associates with long-term outcomes with ixekizumab in radiographic axial spondyloarthritis

S Ramiro, C Lukas, L Bessette, P Wickersham… - RMD open, 2024 - rmdopen.bmj.com
Background The Assessment of SpondyloArthritis international Society-European Alliance of
Associations for Rheumatology recommendations for axial spondyloarthritis (axSpA) …