New concepts for an old problem: the diagnosis of endometrial hyperplasia

PA Sanderson, HOD Critchley… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Endometrial hyperplasia (EH) is a uterine pathology representing a
spectrum of morphological endometrial alterations. It is predominantly characterized by an …

Classification of endometrial carcinoma: more than two types

R Murali, RA Soslow, B Weigelt - The Lancet Oncology, 2014 - thelancet.com
Endometrial cancer is the most common gynaecological malignancy in Europe and North
America. Traditional classification of endometrial carcinoma is based either on clinical and …

Type I and II endometrial cancers: have they different risk factors?

VW Setiawan, HP Yang, MC Pike… - Journal of Clinical …, 2013 - ascopubs.org
Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about …

Endometrial carcinoma: molecular subtypes, precursors and the role of pathology in early diagnosis

J Huvila, J Pors, EF Thompson… - The Journal of …, 2021 - Wiley Online Library
Endometrial carcinoma (EC) is classified into a wide range of morphological variants; this list
has expanded over the past decade with the inclusion of mesonephric‐like and …

A review of immune checkpoint blockade therapy in endometrial cancer

AK Green, J Feinberg, V Makker - American Society of Clinical …, 2020 - ascopubs.org
Approximately 30% of primary endometrial cancers are microsatellite instability
high/hypermutated (MSI-H), and 13% to 30% of recurrent endometrial cancers are MSI-H or …

Use of mutation profiles to refine the classification of endometrial carcinomas

MK McConechy, J Ding, MCU Cheang… - The Journal of …, 2012 - Wiley Online Library
The classification of endometrial carcinomas is based on pathological assessment of tumour
cell type; the different cell types (endometrioid, serous, carcinosarcoma, mixed …

High-grade endometrial carcinomas: morphologic and immunohistochemical features, diagnostic challenges and recommendations

R Murali, B Davidson, O Fadare… - International Journal …, 2019 - journals.lww.com
This review of challenging diagnostic issues concerning high-grade endometrial carcinomas
is derived from the authors' review of the literature followed by discussions at the …

Etiologic heterogeneity in endometrial cancer: evidence from a Gynecologic Oncology Group trial

LA Brinton, AS Felix, DS McMeekin, WT Creasman… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: Although the epidemiology of typical endometrial carcinomas (grades 1–2
endometrioid or Type I) is well established, less is known regarding higher grade …

Evolving roles of histologic evaluation and molecular/genomic profiling in the management of endometrial cancer

R Murali, DF Delair, SM Bean, NR Abu-Rustum… - Journal of the National …, 2018 - jnccn.org
Endometrial cancers are the most common gynecologic malignancies. The staging of
endometrial cancer has evolved from a clinical-based system to a comprehensive surgical …

Preoperative neutrophil: lymphocyte and platelet: lymphocyte ratios predict endometrial cancer survival

M Cummings, L Merone, C Keeble, L Burland… - British journal of …, 2015 - nature.com
Background: Variations in systemic inflammatory response biomarker levels have been
associated with adverse clinical outcome in various malignancies. This study determined the …