[HTML][HTML] Functional roles of non-coding Y RNAs

MP Kowalski, T Krude - The international journal of biochemistry & cell …, 2015 - Elsevier
Non-coding RNAs are involved in a multitude of cellular processes but the biochemical
function of many small non-coding RNAs remains unclear. The family of small non-coding Y …

Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes; implications for the immune system

TAP Driedonks, ENM Nolte-'t Hoen - Frontiers in immunology, 2019 - frontiersin.org
The exchange of extracellular vesicles (EV) between immune cells plays a role in various
immune regulatory processes. EV are nano-sized lipid bilayer-enclosed structures that …

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

AH Buck, G Coakley, F Simbari, HJ McSorley… - Nature …, 2014 - nature.com
In mammalian systems RNA can move between cells via vesicles. Here we demonstrate that
the gastrointestinal nematode Heligmosomoides polygyrus, which infects mice, secretes …

Identification of RNA polymerase III-transcribed genes in eukaryotic genomes

G Dieci, A Conti, A Pagano, D Carnevali - Biochimica et Biophysica Acta …, 2013 - Elsevier
The RNA polymerase (Pol) III transcription system is devoted to the production of short,
generally abundant noncoding (nc) RNAs in all eukaryotic cells. Previously thought to be …

[HTML][HTML] Shortcuts to a functional adipose tissue: The role of small non-coding RNAs

BB Brandao, BA Guerra, MA Mori - Redox biology, 2017 - Elsevier
Metabolic diseases such as type 2 diabetes are a major public health issue worldwide.
These diseases are often linked to a dysfunctional adipose tissue. Fat is a large …

Y RNA: An overview of their role as potential biomarkers and molecular targets in human cancers

C Gulìa, F Signore, M Gaffi, S Gigli, R Votino… - Cancers, 2020 - mdpi.com
Y RNA are a class of small non-coding RNA that are largely conserved. Although their
discovery was almost 40 years ago, their function is still under investigation. This is evident …

Y RNAs: biogenesis, function and implications for the cardiovascular system

N Valkov, S Das - Non-coding RNAs in Cardiovascular Diseases, 2020 - Springer
In recent years, progress in the field of high-throughput sequencing technology and its
application to a wide variety of biological specimens has greatly advanced the discovery …

Are the Ro RNP‐associated Y RNAs concealing microRNAs? Y RNA‐derived miRNAs may be involved in autoimmunity

APM Verhagen, GJM Pruijn - Bioessays, 2011 - Wiley Online Library
Here we discuss the hypothesis that the RNA components of the Ro ribonucleoproteins
(RNPs), the Y RNAs, can be processed into microRNAs (miRNAs). Although Ro RNPs …

The challenging world of extracellular RNAs of helminth parasites

MA Cucher, ME Ancarola, L Kamenetzky - Molecular immunology, 2021 - Elsevier
In the last years, cell free or extracellular RNAs (ex-RNAs) have emerged as novel
intercellular messengers between animal cells, including pathogens. In infectious diseases …

Homology-based annotation of non-coding RNAs in the genomes of Schistosoma mansoni and Schistosoma japonicum

CS Copeland, M Marz, D Rose, J Hertel, PJ Brindley… - BMC genomics, 2009 - Springer
Background Schistosomes are trematode parasites of the phylum Platyhelminthes. They are
considered the most important of the human helminth parasites in terms of morbidity and …