For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …

Cancer is one of the leading causes of morbidity and mortality worldwide, and the discovery
of new drugs for cancer therapy is one of the most important objectives for the …

Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …

Venoms are a rich source of bioactive compounds, and among them is leberagin-C (Leb-C),
a disintegrin-like protein derived from the venom of Macrovipera lebetina …

The human body has a set of physiological processes, known as hemostasis, which keeps
the blood fluid and free of clots in normal vessels; in the case of vascular injury, this process …

Biologically active compounds with potential anticancer activity have been isolated from
various animal sources. Recent research is focused on venoms from animal sources, since …

Various factors, such as geographical origin, climate, sex, age and diet can influence the
composition and pathophysiological activities of snake venoms. In this study, we examined …

Disintegrins are non-enzymatic proteins that interfere on cell–cell interactions and signal
transduction, contributing to the toxicity of snake venoms and play an essential role in …

Disintegrins are a family of small cysteine-rich peptides, found in a wide variety of snake
venoms of different phylogenetic origin. These peptides selectively bind to integrins, which …

Breast cancer is a highly malignant carcinoma and remains the second leading cause of
mortality among women. The antitumor effects of metalloproteinases and disintegrins from …