Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …

Transposable elements (TEs) are a prolific source of tightly regulated, biochemically active
non-coding elements, such as transcription factor-binding sites and non-coding RNAs. Many …

Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

The notion of the “biological individual” is crucial to studies of genetics, immunology,
evolution, development, anatomy, and physiology. Each of these biological subdisciplines …

Since the discovery of transposons, their sheer abundance in host genomes has puzzled
many. While historically viewed as largely harmless 'parasitic'DNAs during evolution …

The fact that transposable elements (TEs) can influence host gene expression was first
recognized more than 50 years ago. However, since that time, TEs have been widely …

The life cycle of endogenous retroviruses (ERVs), also called long terminal repeat (LTR)
retrotransposons, begins with transcription by RNA polymerase II followed by reverse …

Human higher cognition is attributed to the evolutionary expansion and elaboration of the
human cerebral cortex. However, the genetic mechanisms contributing to these …

Human embryos frequently harbor large-scale complex chromosomal errors that impede
normal development. Affected embryos may fail to implant although many first breach the …