Epidemiology and treatment of multiple sclerosis in elderly populations

CB Vaughn, D Jakimovski, KS Kavak… - Nature Reviews …, 2019 - nature.com
The prevalence of multiple sclerosis (MS) and the age of affected patients are increasing
owing to increased longevity of the general population and the availability of effective …

Memantine for dementia

R McShane, AA Sastre… - Cochrane database of …, 2006 - cochranelibrary.com
Memantine for dementia - McShane, R - 2006 | Cochrane Library Skip to Content Cookies Our
site uses cookies to improve your experience. You can find out more about our use of cookies …

[PDF][PDF] Memantine for dementia

R McShane, MJ Westby, E Roberts… - … Database Syst Rev, 2019 - cochranelibrary.com
Cochrane Page 1 Cochrane Library Cochrane Database of Systematic Reviews Memantine
for dementia (Review) McShane R, Westby MJ, Roberts E, Minakaran N, Schneider L …

Molecular mechanisms linking neuroinflammation and neurodegeneration in MS

E Ellwardt, F Zipp - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder of the central
nervous system (CNS) and one of the leading causes of neurological deficits and disability …

[HTML][HTML] Oral memantine for the treatment of glaucoma: design and results of 2 randomized, placebo-controlled, phase 3 studies

RN Weinreb, JM Liebmann, GA Cioffi, I Goldberg… - Ophthalmology, 2018 - Elsevier
Purpose To evaluate the effectiveness and safety of oral memantine as a potential
neuroprotective agent in open-angle glaucoma (OAG) at risk for progression. Design Two …

Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions

AJ Thompson, AT Toosy, O Ciccarelli - The Lancet Neurology, 2010 - thelancet.com
Management of symptoms in multiple sclerosis (MS) has received little attention compared
with disease-modifying treatments. However, the effect of these symptoms on quality of life …

Pharmacotherapy of vestibular and ocular motor disorders, including nystagmus

M Strupp, MJ Thurtell, AG Shaikh, T Brandt, DS Zee… - Journal of …, 2011 - Springer
We review current pharmacological treatments for peripheral and central vestibular
disorders, and ocular motor disorders that impair vision, especially pathological nystagmus …

Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice

JCC de Sa, L Airas, E Bartholome… - Therapeutic …, 2011 - journals.sagepub.com
As more investigations into factors affecting the quality of life of patients with multiple
sclerosis (MS) are undertaken, it is becoming increasingly apparent that certain …

Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities

R Macrez, PK Stys, D Vivien, SA Lipton… - The Lancet …, 2016 - thelancet.com
Research advances support the idea that excessive activation of the glutamatergic pathway
plays an important part in the pathophysiology of multiple sclerosis. Beyond the well …

Multiple sclerosis and glutamate excitotoxicity

M Kostic, N Zivkovic, I Stojanovic - Reviews in the neurosciences, 2013 - degruyter.com
The previous understanding of multiple sclerosis was solely related to neuroinflammation
and its harmful effects; however, countless data indicate the importance of some …