Pain, a prevalent clinical symptom, significantly demands attention in the current public
health system due to its profound impact on patients' quality of life, daily activities, and …

Dried toad skin (TS) and toad venom (TV) are the dried skin of the Bufo bufo gargarizans
Cantor and the Bufo melanostictus Schneider, which remove the internal organs and the …

Transient receptor potential vanillic acid 1 (TRPV1) is an ion channel activated by heat and
inflammatory factors involved in the development of various types of pain. The P2X7 …

Background Postherpetic neuralgia (PHN) is a debilitating complication of herpes zoster,
characterized by persistent neuropathic pain that significantly impairs patients' quality of life …

Severe acute pancreatitis (SAP) is a prevalent acute inflammatory disease that is clinically
manifested by systemic inflammation dysregulation, resulting in a significantly elevated …

Neuropathic pain (NP) is a common, intractable chronic pain caused by nerve dysfunction
and primary lesion of the nervous system. The etiology and pathogenesis of NP have not yet …

Microspheres are commonly implemented in drug delivery system to enhance drug
bioactivity and reduce the toxicity. Membrane emulsification is a promising technique to be …

The Vitamin D receptor (VDR) is a crucial nuclear receptor that plays a vital role in various
physiological functions. To a larger extent, the genomic effects of VDR maintain general …

In this study, we developed a green and multifunctional bioactive nanoemulsion (BBG-NEs)
of Blumea balsamifera oil using Bletilla striata polysaccharide (BSP) and glycyrrhizic acid …

For many years, there has been ongoing research on the P2X7 receptor (P2X7R). A
comprehensive, systematic, and objective evaluation of the scientific output and status of …