In the context of impact on human health, nitrite/nitrate and related nitrogen species such as
nitric oxide (NO) are a matter of increasing scientific controversy. An increase in the content …

Nitric oxide (NO), generated from L-arginine and oxygen by NO synthases, is a pleiotropic
signaling molecule involved in cardiovascular and metabolic regulation. More recently, an …

Prevalence of diabetes, a serious public health problem is rapidly increasing worldwide.
Type-2 diabetes is the common form of diabetes characterized by insulin resistance and …

In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

The salivary glands and oral bacteria play an essential role in the conversion process from
nitrate (NO3-) and nitrite (NO2-) to nitric oxide (NO) in the human body. NO is, at present …

Current research has described improving multisystem disease and organ function through
dietary nitrate (DN) supplementation. They have provided some evidence that these floras …

Recent research demonstrates a reciprocal relationship between gut microbiota-derived
metabolites and the host in controlling the energy homeostasis in mammals. On the one …

Purpose Supplementation with inorganic nitrate to boost the nitrate-nitrite-nitric oxide (NO)
pathway, may act as a potential therapeutic agent in diabetes. The aim of this study was to …

Prevalence of obesity is increasing worldwide and type 2 diabetes to date is the most
devastating complication of obesity. Decreased nitric oxide bioavailability is a feature of …

The potential effects of inorganic nitrate/nitrite on global health are a much debated issue. In
addition to possible methemoglobinemia and carcinogenic properties, anti-thyroid effects of …