D Shungin, TW Winkler, DC Croteau-Chonka… - Nature, 2015 - nature.com
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic …
PT Brown, AM Handorf, W Bae Jeon… - Current pharmaceutical …, 2013 - ingentaconnect.com
The field of regenerative medicine and tissue engineering is an ever evolving field that holds promise in treating numerous musculoskeletal diseases and injuries. An important impetus …
LN Reynard, C Bui, CM Syddall, J Loughlin - Human genetics, 2014 - Springer
GDF5 encodes an extracellular signalling molecule that is essential for normal skeletal development. The rs144383 C to T SNP located in the 5ʹUTR of this gene is functional and …
D Xiao, F Yang, Q Zhao, S Chen, F Shi, X Xiang… - RSC …, 2018 - pubs.rsc.org
Synthetic scaffolds with multifunctional properties, including angiogenesis and osteogenesis capacities, play an essential role in accelerating bone regeneration. In this study, various …
KG Lombana, LR Goodrich, JN Phillips… - Frontiers in Veterinary …, 2015 - frontiersin.org
Diseases of the musculoskeletal system are a major cause of loss of use and retirement in sport horses. The use of bone marrow-derived mesenchymal stem cells (BMDMSCs) for …
B Zhang, Q Luo, A Halim, Y Ju… - Current Stem Cell …, 2017 - ingentaconnect.com
Background: Tendon is composed of connective tissue, is able to retract with high tensile force, and plays a significant role in musculoskeletal motion. However, inappropriate …
M Wang, J Wu, P Wu, Y Li - Genes & Diseases, 2023 - Elsevier
Circular RNAs (circRNAs) are a novel class of noncoding RNAs that widely exist in eukaryotes. As a new focus in the field of molecular regulation, circRNAs have attracted …
C Granéli, C Karlsson, H Brisby, A Lindahl… - Connective tissue …, 2014 - Taylor & Francis
Mesenchymal stem cells (MSCs) can differentiate into several cell types, such as osteoblasts and adipocytes, both in vitro and in vivo. Although these two differentiation pathways are …