Investigation of the MDM2-binding potential of de novo designed peptides using enhanced sampling simulations
The tumor suppressor p53 plays a crucial role in cellular responses to various stresses,
regulating key processes such as apoptosis, senescence, and DNA repair. Dysfunctional …
regulating key processes such as apoptosis, senescence, and DNA repair. Dysfunctional …
Csc01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach
About 30% of malignant tumors include KRAS mutations, which are frequently required for
the development and maintenance of malignancies. KRAS is now a top-priority cancer target …
the development and maintenance of malignancies. KRAS is now a top-priority cancer target …
Revolutionizing drug discovery: an AI-powered transformation of molecular docking
AA Fadahunsi, HO Uzoeto, NO Okoro… - Medicinal Chemistry …, 2024 - Springer
AI-based molecular docking, a computational technique fueled by artificial intelligence (AI)
algorithms, is transforming the landscape of drug discovery. This method, crucial for …
algorithms, is transforming the landscape of drug discovery. This method, crucial for …