Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties …

D Babadi, S Dadashzadeh, M Osouli… - Journal of controlled …, 2020 - Elsevier
The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Chemico-Biological …, 2022 - Elsevier
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …

Pulmonary targeting of inhalable moxifloxacin microspheres for effective management of tuberculosis

B Vishwa, A Moin, DV Gowda, SMD Rizvi… - Pharmaceutics, 2021 - mdpi.com
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …

Organometallic assembling of chitosan‐Iron oxide nanoparticles with their antifungal evaluation against Rhizopus oryzae

S Saqib, W Zaman, F Ullah, I Majeed… - Applied …, 2019 - Wiley Online Library
The ever‐increasing resistance of plant microbes towards fungicides and bactericides has
been causing serious threat to plant production in recent years. For the development of an …

Role of chitosan based nanomedicines in the treatment of chronic respiratory diseases

N Gulati, K Dua, H Dureja - International journal of biological …, 2021 - Elsevier
Chitosan-loaded nanomedicines provide a greater opportunity for the treatment of
respiratory diseases. Natural biopolymer chitosan and its derivatives have a large number of …

Novel tetrahydrocurcumin integrated mucoadhesive nanocomposite κ-carrageenan/xanthan gum sponges: a strategy for effective local treatment of oral cancerous …

SA Elbanna, HMK Ebada, OY Abdallah… - Drug Delivery, 2023 - Taylor & Francis
Oral cancer is one of the leading causes of death worldwide. Oral precancerous lesions
(OPL) are the precursors of oral cancer, with varying degrees of progression …

Mechanisms for oral absorption enhancement of drugs by nanocrystals

J Liu, L Tu, M Cheng, J Feng, Y Jin - Journal of Drug Delivery Science and …, 2020 - Elsevier
Currently, numerous new compounds suffer from poor water solubility, hindering their oral
absorption from the gastrointestinal tract and thereby limiting their clinical application …

Novel rhein–phospholipid complex targeting skin diseases: development, in vitro, ex vivo, and in vivo studies

HMK Ebada, MMA Nasra, YSR Elnaggar… - Drug delivery and …, 2021 - Springer
Rhein (RH), an anthraquinone derivative, has proven to be a promising molecule for treating
several skin disorders thanks to its pleiotropic pharmacological activities like antimicrobial …

Development and optimization of hybrid polymeric nanoparticles of apigenin: Physicochemical characterization, antioxidant activity and cytotoxicity evaluation

A Zafar, NK Alruwaili, SS Imam, OA Alsaidan… - Sensors, 2022 - mdpi.com
Breast cancer is the most common cancer in females and ranked second after skin cancer.
The use of natural compounds is a good alternative for the treatment of breast cancer with …

Cationic nanocarrier of rhein based on hydrophobic ion pairing approach as intra-articular targeted regenerative therapy for osteoarthritis

HMK Ebada, MMA Nasra, RA Nassra… - Colloids and Surfaces B …, 2022 - Elsevier
Cartilage deterioration is the hallmark of osteoarthritis (OA). Rapid clearance of intra-
articularly injected drugs and inherent cartilage barrier properties represent enormous …