Formation and function of sperm tail structures in association with sperm motility defects

MS Lehti, A Sironen - Biology of reproduction, 2017 - academic.oup.com
Male infertility is an increasing problem partly due to inherited genetic variations. Mutations
in genes involved in formation of the sperm tail cause motility defects and thus male …

Genetic dissection of mammalian fertility pathways

MM Matzuk, DJ Lamb - Nature Medicine, 2002 - nature.com
The world's population is increasing at an alarming rate and is projected to reach nine billion
by 2050. Despite this, 15% of couples world-wide remain childless because of infertility. Few …

A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets

N Schultz, FK Hamra… - Proceedings of the …, 2003 - National Acad Sciences
Understanding mammalian spermatozoan development and the events surrounding
fertilization has grown slowly, in part because of uncertainty about the number and identity of …

Fertilization: a sperm's journey to and interaction with the oocyte

M Ikawa, N Inoue, AM Benham… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Mammalian fertilization comprises sperm migration through the female reproductive tract,
biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct …

The spermatozoon

EM Eddy, D O'brien - Knobil and Neill's physiology of …, 2006 - books.google.com
This chapter examines the novel structural features of the spermatozoon, their composition
and assembly, and the mechanisms regulating their function. The spermatozoon is a highly …

Roles of reactive oxygen species in the spermatogenesis regulation

G Guerriero, S Trocchia, FK Abdel-Gawad… - Frontiers in …, 2014 - frontiersin.org
Spermatogenesis is a complex process of male germ cells proliferation and maturation from
diploid spermatogonia, through meiosis, to mature haploid spermatozoa. The process …

[HTML][HTML] The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review

AG Mukherjee, AV Gopalakrishnan - Ecotoxicology and Environmental …, 2023 - Elsevier
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …

Identification of mouse sperm SED1, a bimotif EGF repeat and discoidin-domain protein involved in sperm-egg binding

MA Ensslin, BD Shur - Cell, 2003 - cell.com
We report the identification of SED1, a protein required for mouse sperm binding to the egg
zona pellucida. SED1 is homologous to a small group of secreted cell-matrix adhesive …

Selenium in mammalian spermiogenesis

L Flohé - 2007 - degruyter.com
The role of selenium in male fertility is reviewed with special emphasis on selenoprotein P
and phospholipid hydroperoxide glutathione peroxidase (GPx4) in spermiogenesis. Inverse …

Review on molecular and biochemical insights of arsenic-mediated male reproductive toxicity

K Renu, H Madhyastha, R Madhyastha, M Maruyama… - Life sciences, 2018 - Elsevier
Arsenic is a natural metalloid found in abundance, in the environment. Exposure to arsenic
can cause health issues due to its carcinogenic nature. The primary source of arsenic …