DNA methylation, ie, addition of methyl group to 5′-carbon of cytosine residues in CpG
dinucleotides, is an important epigenetic modification regulating gene expression, and thus …

Methylation of cytosine at the 5-position is a common epigenetic modification in mammalian
DNA and plays an important role in regulating gene expression. Oxidized derivatives of 5 …

DNA methylation is an important epigenetic modification in human genomes. Herein, we
develop a single quantum dot (QD)-based nanosensor for sensitive detection of DNA …

DNA methyltransferases (MTases), a family of enzymes that catalyse the methylation of
DNA, have a profound effect on gene regulation. A large body of evidence has indicated that …

DNA methylation is an epigenetic modification of DNA, where a methyl group is added at the
fifth carbon of the cytosine base to form 5 methyl cytosine (5mC) without altering the DNA …

DNA methylation has become a promising epigenetic biomarker for cancer diagnosis,
prognosis, and therapy monitoring. Herein, we demonstrate for the first time the …

Epigenetic inheritance is a heritable change in gene function independent of alterations in
nucleotide sequence. It regulates the normal cellular activities of the organisms by affecting …

This paper reports a simple electrochemical strategy for the determination of microRNAs
(miRNAs) using a commercial His-Tag-Zinc finger protein (His-Tag-ZFP) that binds …

On the basis of the different diffusivity and existence of electrostatic repulsion between long
and short DNA on the negatively changed indium tin oxide (ITO) microelectrode, a simple …

Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor with high prevalence
in southern China. Aberrant DNA methylation, as a hallmark of cancer, is extensively present …