Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors

T Pillaiyar, M Manickam… - Journal of enzyme …, 2017 - Taylor & Francis
Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Ectoine as a promising protective agent in humans and animals

A Bownik, Z Stępniewska - Arhiv za higijenu rada i toksikologiju, 2016 - hrcak.srce.hr
Sažetak Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced
by several bacterial species in response to osmotic stress and unfavourable environmental …

Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia

JWF Law, V Letchumanan… - … In Microbes & …, 2023 - journals.hh-publisher.com
Streptomyces learnhanii sp. nov. MUM 203J T was isolated from Malaysia mangrove soil.
This Gram-positive bacterium produces pale greenish-yellow aerial and greyish-yellow …

Streptomyces griseiviridis sp. nov., a novel “modern actinobacteria” isolated from Malaysia mangrove soil

JWF Law, LTH Tan, V Letchumanan… - … in Microbes and …, 2023 - research.monash.edu
A novel strain, Streptomyces griseiviridis MUM 136J T was recovered from a mangrove
forest soil in Malaysia. The Gram-positive bacterium forms strong yellow aerial mycelium …

The skin-whitening effects of ectoine via the suppression of α-MSH-stimulated melanogenesis and the activation of antioxidant Nrf2 pathways in UVA-irradiated …

YC Hseu, XZ Chen, Y Vudhya Gowrisankar, HR Yen… - Antioxidants, 2020 - mdpi.com
Ultraviolet A (UVA)-irradiation induced reactive oxygen species (ROS) production mediates
excessive melanogenesis in skin cells leading to pigmentation. We demonstrated the …

Fermented broth in tyrosinase-and melanogenesis inhibition

CF Chan, CC Huang, MY Lee, YS Lin - Molecules, 2014 - mdpi.com
Fermented broth has a long history of applications in the food, pharmaceutical and cosmetic
industries. Recently, the use of fermented broth in skin care products is in ascendance. This …

Bioactivity profiling of the extremolyte ectoine as a promising protectant and its heterologous production

Z Ma, C Wu, L Zhu, R Chang, W Ma, Y Deng, X Chen - 3 Biotech, 2022 - Springer
Ectoine is a compatible solutes that is diffusely dispersed in bacteria and archaea. It plays a
significant role as protectant against various external pressures, such as high temperature …

Production and recovery of ectoine: A review of current state and future prospects

HS Ng, PK Wan, A Kondo, JS Chang, JCW Lan - Processes, 2023 - mdpi.com
Ectoine (1, 4, 5, 6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a revolutionizing
substance with vast applications in the cosmetic and food industries. Ectoine is often …

Functionality study of santalin as tyrosinase inhibitor: A potential depigmentation agent

H Hridya, A Amrita, S Mohan, M Gopalakrishnan… - International journal of …, 2016 - Elsevier
Excessive melanin production leads to hyperpigmentation disorders which results in
distressing aesthetic values. Though there are some synthetic depigmentation agents …

Natural product rhynchophylline prevents stress-induced hair graying by preserving melanocyte stem cells via the β2 adrenergic pathway suppression

X Li, R Shi, L Yan, W Chu, R Sun, B Zheng… - Natural Products and …, 2023 - Springer
Norepinephrine (NA), a stress hormone, can accelerate hair graying by binding to β2
adrenergic receptors (β2AR) on melanocyte stem cells (McSCs). From this, NA-β2AR axis …