Metabonomics of human colorectal cancer: new approaches for early diagnosis and biomarker discovery

Y Ni, G Xie, W Jia - Journal of proteome research, 2014 - ACS Publications
Colorectal cancer (CRC) is one of the most common cancers in the world, having both high
prevalence and mortality. It is usually diagnosed at advanced stages due to the limitations of …

CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease

S Spataro, C Guerra, A Cavalli, J Sgrignani… - The FEBS …, 2023 - Wiley Online Library
CEMIP (cell migration‐inducing protein), also known as KIAA1199 or HYBID, is a protein
involved in the depolymerisation of hyaluronic acid (HA), a major glycosaminoglycan …

Validation of a Real-Time PCR–Based Qualitative Assay for the Detection of Methylated SEPT9 DNA in Human Plasma

NT Potter, P Hurban, MN White, KD Whitlock… - Clinical …, 2014 - academic.oup.com
BACKGROUND Epi proColon® is a new blood-based colorectal cancer (CRC) screening
test designed to determine the methylation status of a promoter region of the SEPT9 (septin …

A panel of genes methylated with high frequency in colorectal cancer

SM Mitchell, JP Ross, HR Drew, T Ho, GS Brown… - BMC cancer, 2014 - Springer
Background The development of colorectal cancer (CRC) is accompanied by extensive
epigenetic changes, including frequent regional hypermethylation particularly of gene …

[HTML][HTML] The emerging role of KIAA1199 in cancer development and therapy

J Liu, W Yan, P Han, D Tian - Biomedicine & Pharmacotherapy, 2021 - Elsevier
KIAA1199, also known as CEMIP or HYBID, is an important member of the Human
Unidentified Gene-Encoded (HUGE) database. Accumulated evidence has revealed that …

A two-gene blood test for methylated DNA sensitive for colorectal cancer

SK Pedersen, RT Baker, A McEvoy, DH Murray… - PloS one, 2015 - journals.plos.org
Background Specific genes are methylated with high frequency in colorectal neoplasia, and
may leak into blood. Detection of multiple methylated DNA biomarkers in blood may improve …

CEMIP, a promising biomarker that promotes the progression and metastasis of colorectal and other types of cancer

K Domanegg, JP Sleeman, A Schmaus - Cancers, 2022 - mdpi.com
Simple Summary CEMIP (cell migration-inducing and hyaluronan-binding protein) has been
implicated in the pathogenesis of numerous diseases, including colorectal and other forms …

Plasma methylated septin 9: a colorectal cancer screening marker

B Molnár, K Tóth, BK Barták… - Expert review of molecular …, 2015 - Taylor & Francis
Colorectal cancer (CRC) is a slow-developing cancer (10–15 years) with one of the highest
frequencies in the world's population. Many countries have implemented various CRC …

Combined use of CEMIP and CA 19-9 enhances diagnostic accuracy for pancreatic cancer

HS Lee, CY Jang, SA Kim, SB Park, DE Jung, BO Kim… - Scientific reports, 2018 - nature.com
Abstract Carbohydrate antigen (CA) 19-9 is the only diagnostic marker used in pancreatic
cancer despite its limitations. Here, we aimed to identify the diagnostic role of CEMIP (also …

Identification of potential metabolite markers for colon cancer and rectal cancer using serum metabolomics

J Wu, M Wu, Q Wu - Journal of Clinical Laboratory Analysis, 2020 - Wiley Online Library
Background To determine the metabolic characteristics of patients with colon cancer (CC)
and rectal cancer (RC) using gas chromatography‐mass spectrometry (GC‐MS)‐based …