Nutrigenetics, epigenetics and gestational diabetes: consequences in mother and child

M Franzago, F Fraticelli, L Stuppia, E Vitacolonna - Epigenetics, 2019 - Taylor & Francis
ABSTRACT Gestational Diabetes Mellitus (GDM) is the most common metabolic condition
during pregnancy and may result in short-and long-term complications for both mother and …

Epigenetic inheritance and the missing heritability

M Trerotola, V Relli, P Simeone, S Alberti - Human genomics, 2015 - Springer
Genome-wide association studies of complex physiological traits and diseases consistently
found that associated genetic factors, such as allelic polymorphisms or DNA mutations, only …

Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

Epigenetics and lifestyle

JA Alegría-Torres, A Baccarelli, V Bollati - Epigenomics, 2011 - Taylor & Francis
The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …

The role of cigarette smoke-induced epigenetic alterations in inflammation

D Zong, X Liu, J Li, R Ouyang, P Chen - Epigenetics & Chromatin, 2019 - Springer
Background Exposure to cigarette smoke (CS) is a major threat to human health worldwide.
It is well established that smoking increases the risk of respiratory diseases, cardiovascular …

Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia

L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

MicroRNAs as potential signatures of environmental exposure or effect: a systematic review

K Vrijens, V Bollati, TS Nawrot - Environmental health …, 2015 - ehp.niehs.nih.gov
Background: The exposome encompasses all life-course environmental exposures from the
prenatal period onward that influence health. MicroRNAs (miRNAs) are interesting entities …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

The omniscient placenta: metabolic and epigenetic regulation of fetal programming

BM Nugent, TL Bale - Frontiers in neuroendocrinology, 2015 - Elsevier
Fetal development could be considered a sensitive period wherein exogenous insults and
changes to the maternal milieu can have long-term impacts on developmental programming …

MicroRNAs in human placental development and pregnancy complications

G Fu, J Brkić, H Hayder, C Peng - International journal of molecular …, 2013 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical
posttranscriptional regulators of gene expression by promoting mRNA degradation and …