The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …

Viroporins possess important potential as antiviral targets due to their critical roles during
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …

Currently, smallpox, caused by the variola virus belonging to the poxvirus family, has been
completely eradicated according to the WHO. However, other representatives of poxviruses …

Transition metal-catalyzed asymmetric nitrene transfer is a powerful method to generate
enantioenriched amines found in natural products and bioactive molecules. A highly chemo …

A growing interest in pharmacology has made heterocyclic chemistry as one of the emerging
branches of organic chemistry. Piperazine is an excellent heterocycle that possesses a large …

The formation of one unavoidable byproduct in traditional disproportionation reactions limits
their applications in synthesis. Inspired by convergent disproportionation, we develop an …

Sterically hindered cage substrates with exo-and endocyclic double bonds were first used
as substrates in the intramolecular reductive Heck reaction. The Pd (II) complex with an …

Efficient methods for introducing various substituents into the α-position of ethyl 5-
oxohomoadamantyl-4-carboxylate are reported. An unexpected acid-catalysed 1, 2-alkyl …

A new synthesis of racemic 1, 2-diaminoadamantane was accomplished, its resolution into
enantiomers through diastereomeric salts with l-tartaric acid was carried out, which gave …

Substituted ethyl 5-oxohomoadamantane-4-carboxylates were subjected to reactions with
several nucleophiles to establish some aspects of the carbonyl reactivity. However, only one …