Neurostimulation enables adjustable and reversible modulation of disease symptoms,
including those of epilepsy. Two types of brain neuromodulation, comprising anterior …

The few reported controlled studies show that bilateral stimulation of the globus pallidus
interna (GPi) is a safe and effective long-term treatment for hyperkinetic disorders. However …

Globus pallidus internus deep brain stimulation (GPi DBS) is the most effective intervention
for medically refractory segmental and generalized dystonia in both children and adults …

Myoclonus is a sudden, brief, involuntary muscle jerk. It is caused by abrupt muscle
contraction, in the case of positive myoclonus, or by sudden cessation of ongoing muscular …

There is substantial variability in the responsiveness of dystonia patients to deep brain
stimulation (DBS), presumably due to the multiple causes of dystonia. This article presents …

Pallidal deep brain stimulation (DBS) is an established treatment option for medically
refractive dystonia. The mechanism by which globus pallidus pars interna (GPi) DBS …

Presently, 17 distinct monogenic primary dystonias referred to as dystonias 1–4, 5a, b, 6–8,
10–13 and 15–18 (loci DYT 1–4, 5a, b, 6–8, 10–13, 15–18) have been recognized. Twelve …

Our knowledge of the clinical, neurophysiological, and genetic aspects of myoclonus‐
dystonia (M‐D) has improved markedly in the recent years. Basic research has provided …

Deep brain stimulation (DBS) of the internal globus pallidus (GPi) and ventral intermediate
thalamic nucleus (VIM) are established treatment options in primary dystonia and tremor …

Object. Adjusting electrical parameters used in deep brain stimulation (DBS) for dystonia
remains time consuming and is currently based on clinical observation alone. The goal of …