Cyclodextrin–drug inclusion complexes: In vivo and in vitro approaches

SB Carneiro, FI Costa Duarte, L Heimfarth… - International journal of …, 2019 - mdpi.com
This review aims to provide a critical review of the biological performance of natural and
synthetic substances complexed with cyclodextrins, highlighting:(i) inclusion complexes with …

Linalool bioactive properties and potential applicability in drug delivery systems

I Pereira, P Severino, AC Santos, AM Silva… - Colloids and Surfaces B …, 2018 - Elsevier
The medicinal properties of essential oils from aromatic plants are known since antiquity.
Currently, the technological innovation enabled the reinvention of the ancient plant …

Analgesic potential of terpenes derived from Cannabis sativa

E Liktor-Busa, A Keresztes, J LaVigne… - Pharmacological …, 2021 - ASPET
Pain prevalence among adults in the United States has increased 25% over the past two
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …

[HTML][HTML] Cyclodextrins as an encapsulation molecular strategy for volatile organic compounds—Pharmaceutical applications

AC Paiva-Santos, L Ferreira, D Peixoto, F Silva… - Colloids and Surfaces B …, 2022 - Elsevier
The use of essential oils has gained importance due to their wide range of biological
properties. Essential oils comprise a complex mixture of volatile organic compounds (VOCs) …

Inclusion of terpenes in cyclodextrins: Preparation, characterization and pharmacological approaches

PSS Lima, AM Lucchese, HG Araujo-Filho… - Carbohydrate …, 2016 - Elsevier
Terpenes constitute the largest class of natural products and are important resources for the
pharmaceutical, food and cosmetics industries. However, due to their low water solubility …

Monoterpenes as a renewable source of biologically active compounds

NF Salakhutdinov, KP Volcho… - Pure and Applied …, 2017 - degruyter.com
Monoterpenes and their derivatives play an important role in the creation of new biologically
active compounds including drugs. The review focuses on the data on various types of …

Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice

AM Sabogal-Guáqueta, E Osorio… - …, 2016 - Elsevier
Alzheimer's disease (AD) is an age-related progressive neurodegenerative disorder.
Several types of treatments have been tested to block or delay the onset of the disease, but …

Effects of monoterpenes on ion channels of excitable cells

M Oz, Y Lozon, A Sultan, KHS Yang… - Pharmacology & …, 2015 - Elsevier
Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of
plant-derived 'essential oils'. Monoterpenes such as menthol, carvacrol, and eugenol have …

The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3. 2 T-type calcium channels

VM Gadotti, S Huang, GW Zamponi - Molecular brain, 2021 - Springer
T-type calcium channels are known molecular targets of certain phytocannabinoids and
endocannabinoids. Here we explored the modulation of Cav3. 2 T-type calcium channels by …

[HTML][HTML] Anti-inflammatory activity of the essential oil obtained from Ocimum basilicum complexed with β-cyclodextrin (β-CD) in mice

LB Rodrigues, AOBPB Martins, J Ribeiro-Filho… - Food and Chemical …, 2017 - Elsevier
Cyclodextrins (CDs) are cyclic oligosaccharides can enhance the bioavailability of drugs.
Ocimum basilicum is an aromatic plant found in Brazil used in culinary. The essential oil of …