Detection of pathogenic bacteria via nanomaterials-modified aptasensors

S Sharifi, SZ Vahed, E Ahmadian, SM Dizaj… - Biosensors and …, 2020 - Elsevier
Detection and identification of special cells via aptamer-based nano-conjugates sensors
have been revolutionized over the past few years. These sensing platforms rely on selecting …

Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers

S Surappa, P Multani, U Parlatan, PD Sinawang… - Lab on a Chip, 2023 - pubs.rsc.org
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …

Nanoparticle amplification labeling for high-performance magnetic cell sorting

Z Wang, H Wang, S Lin, S Ahmed, S Angers… - Nano …, 2022 - ACS Publications
Magnetic cell sorting is an enabling tool for the isolation of specific cellular subpopulations
for downstream applications and requires the cells to be labeled by a sufficient number of …

Recent advances in aptamer-based biosensors for global health applications

LA Stanciu, Q Wei, AK Barui… - Annual Review of …, 2021 - annualreviews.org
Since aptamers were first reported in the early 2000s, research on their use for the detection
of health-relevant analytical targets has exploded. This review article provides a brief …

Microfluidic systems for cancer diagnosis and applications

S Akgönüllü, M Bakhshpour, AK Pişkin, A Denizli - Micromachines, 2021 - mdpi.com
Microfluidic devices have led to novel biological advances through the improvement of micro
systems that can mimic and measure. Microsystems easily handle sub-microliter volumes …

Tracking the expression of therapeutic protein targets in rare cells by antibody-mediated nanoparticle labelling and magnetic sorting

M Labib, Z Wang, SU Ahmed, RM Mohamadi… - Nature biomedical …, 2021 - nature.com
Molecular-level features of tumours can be tracked using single-cell analyses of circulating
tumour cells (CTCs). However, single-cell measurements of protein expression for rare …

Circulating tumor cell profiling for precision oncology

M Labib, SO Kelley - Molecular oncology, 2021 - Wiley Online Library
Analysis of circulating tumor cells (CTCs) collected from patient's blood offers a broad range
of opportunities in the field of precision oncology. With new advances in profiling technology …

PillarX: a microfluidic device to profile circulating tumor cell clusters based on geometry, deformability, and epithelial state

BJ Green, M Marazzini, B Hershey, A Fardin, Q Li… - Small, 2022 - Wiley Online Library
Circulating tumor cell (CTC) clusters are associated with increased metastatic potential and
worse patient prognosis, but are rare, difficult to count, and poorly characterized …

Microfluidics for studying metastatic patterns of lung cancer

M Ruzycka, MR Cimpan, I Rios-Mondragon… - Journal of …, 2019 - Springer
The incidence of lung cancer continues to rise worldwide. Because the aggressive
metastasis of lung cancer cells is the major drawback of successful therapies, the crucial …

Magnetically driven microfluidics for isolation of circulating tumor cells

L Luo, Y He - Cancer Medicine, 2020 - Wiley Online Library
Circulating tumor cells (CTCs) largely contribute to cancer metastasis and show potential
prognostic significance in cancer isolation and detection. Miniaturization has progressed …