Antimicrobial susceptibility testing: a comprehensive review of currently used methods

I Gajic, J Kabic, D Kekic, M Jovicevic, M Milenkovic… - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance (AMR) has emerged as a major threat to public health globally.
Accurate and rapid detection of resistance to antimicrobial drugs, and subsequent …

[HTML][HTML] The role of vaccines in combatting antimicrobial resistance

F Micoli, F Bagnoli, R Rappuoli, D Serruto - Nature Reviews …, 2021 - nature.com
The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

Modern tools for rapid diagnostics of antimicrobial resistance

A Vasala, VP Hytönen, OH Laitinen - Frontiers in cellular and infection …, 2020 - frontiersin.org
Fast, robust, and affordable antimicrobial susceptibility testing (AST) is required, as roughly
50% of antibiotic treatments are started with wrong antibiotics and without a proper …

Innovative and rapid antimicrobial susceptibility testing systems

A van Belkum, CAD Burnham, JWA Rossen… - Nature Reviews …, 2020 - nature.com
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …

Next-generation nanophotonic-enabled biosensors for intelligent diagnosis of SARS-CoV-2 variants

BA Taha, Y Al Mashhadany, Q Al-Jubouri… - Science of The Total …, 2023 - Elsevier
Constantly mutating SARS-CoV-2 is a global concern resulting in COVID-19 infectious
waves from time to time in different regions, challenging present-day diagnostics and …

A fast impedance-based antimicrobial susceptibility test

DC Spencer, TF Paton, KT Mulroney, TJJ Inglis… - Nature …, 2020 - nature.com
There is an urgent need to develop simple and fast antimicrobial susceptibility tests (ASTs)
that allow informed prescribing of antibiotics. Here, we describe a label-free AST that can …

EUCAST rapid antimicrobial susceptibility testing (RAST) in blood cultures: validation in 55 European laboratories

A Åkerlund, E Jonasson, E Matuschek… - Journal of …, 2020 - academic.oup.com
Objectives When bloodstream infections are caused by resistant bacteria, rapid
antimicrobial susceptibility testing (RAST) is important for adjustment of therapy. The …

Deep learning analysis of vibrational spectra of bacterial lysate for rapid antimicrobial susceptibility testing

WJ Thrift, S Ronaghi, M Samad, H Wei, DG Nguyen… - ACS …, 2020 - ACS Publications
Rapid antimicrobial susceptibility testing (AST) is an integral tool to mitigate the unnecessary
use of powerful and broad-spectrum antibiotics that leads to the proliferation of multi-drug …

Bloodstream infections–Standard and progress in pathogen diagnostics

B Lamy, M Sundqvist, EA Idelevich - Clinical Microbiology and Infection, 2020 - Elsevier
Background Bloodstream infection (BSI) is a major public health burden worldwide, with
high mortality. Patient outcome is critically influenced by delayed therapy, and fast and …

The antibiogram: key considerations for its development and utilization

WR Truong, L Hidayat, MA Bolaris… - JAC-antimicrobial …, 2021 - academic.oup.com
The antibiogram is an essential resource for institutions to track changes in antimicrobial
resistance and to guide empirical antimicrobial therapy. In this Viewpoint, data and …