Breast cancer: conventional diagnosis and treatment modalities and recent patents and technologies

MI Nounou, F ElAmrawy, N Ahmed… - Breast cancer: basic …, 2015 - journals.sagepub.com
Breast cancer is the most prevalent cancer among women worldwide. However, increased
survival is due to the dramatic advances in the screening methods, early diagnosis, and …

Hybrid models of tumor growth

KA Rejniak, ARA Anderson - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
Cancer is a complex, multiscale process in which genetic mutations occurring at a
subcellular level manifest themselves as functional changes at the cellular and tissue scale …

A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition

C Gong, O Milberg, B Wang, P Vicini… - Journal of the …, 2017 - royalsocietypublishing.org
When the immune system responds to tumour development, patterns of immune infiltrates
emerge, highlighted by the expression of immune checkpoint-related molecules such as …

Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression

P Macklin, ME Edgerton, AM Thompson… - Journal of theoretical …, 2012 - Elsevier
Ductal carcinoma in situ (DCIS)—a significant precursor to invasive breast cancer—is
typically diagnosed as microcalcifications in mammograms. However, the effective use of …

Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues

A Karolak, DA Markov… - Journal of The …, 2018 - royalsocietypublishing.org
A main goal of mathematical and computational oncology is to develop quantitative tools to
determine the most effective therapies for each individual patient. This involves predicting …

Toward predictive multiscale modeling of vascular tumor growth: computational and experimental oncology for tumor prediction

JT Oden, EABF Lima, RC Almeida, Y Feng… - … Methods in Engineering, 2016 - Springer
New directions in medical and biomedical sciences have gradually emerged over recent
years that will change the way diseases are diagnosed and treated and are leading to the …

Cellular modeling of cancer invasion: integration of in silico and in vitro approaches

Y Kam, KA Rejniak… - Journal of cellular …, 2012 - Wiley Online Library
Cancer invasion is one of the hallmarks of cancer and a prerequisite for cancer metastasis.
However, the invasive process is very complex, depending on multiple correlated intrinsic …

Emergence of microstructural patterns in skin cancer: a phase separation analysis in a binary mixture

C Chatelain, T Balois, P Ciarletta… - New Journal of …, 2011 - iopscience.iop.org
Clinical diagnosis of skin cancers is based on several morphological criteria, among which
is the presence of microstructures (eg dots and nests) sparsely distributed within the tumour …

An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia

KA Norton, T Wallace, NB Pandey, AS Popel - BMC systems biology, 2017 - Springer
Background Triple-negative breast cancer lacks estrogen, progesterone, and HER2
receptors and is thus not possible to treat with targeted therapies for these receptors …

[图书][B] An introduction to physical oncology: How mechanistic mathematical modeling can improve cancer therapy outcomes

V Cristini, E Koay, Z Wang - 2017 - books.google.com
Physical oncology has the potential to revolutionize cancer research and treatment. The
fundamental rationale behind this approach is that physical processes, such as transport …