Characterization of heterozygosity-rich regions in Italian and worldwide goat breeds

G Chessari, A Criscione, D Marletta, P Crepaldi… - Scientific Reports, 2024 - nature.com
Heterozygosity-rich regions (HRR) are genomic regions of high heterozygosity, which may
harbor loci related to key functional traits such as immune response, survival rate, fertility …

[HTML][HTML] Selection for resilience in livestock production systems

H Laghouaouta, LJ Fraile, RN Pena - International Journal of Molecular …, 2024 - mdpi.com
Selective breeding for improved animal resilience is becoming critical to increase the
sustainability of production systems. Despite the existence of a genetic component for …

[HTML][HTML] Genomic signatures for drylands adaptation at gene-rich regions in African zebu cattle

A Tijjani, B Salim, MVB da Silva, HA Eltahir, TH Musa… - Genomics, 2022 - Elsevier
Abstract Background Indigenous Sudanese cattle are mainly indicine/zebu (humped) type.
They thrive in the harshest dryland environments characterised by high temperatures, long …

[PDF][PDF] Structural variant landscapes reveal convergent signatures of evolution in sheep and goats

J Yang, DF Wang, JH Huang, QH Zhu, LY Luo, R Lu… - Genome Biology, 2024 - Springer
Background Sheep and goats have undergone domestication and improvement to produce
similar phenotypes, which have been greatly impacted by structural variants (SVs). Here, we …

Comparative transcriptional analysis identifies genes associated with the attenuation of Theileria parva infected cells after long-term in vitro culture

EMDL van der Heijden, L Lefevre, A Gossner… - Scientific Reports, 2024 - nature.com
Autologous administration of attenuated Theileria parva-infected cells induces immunity to T.
parva in cattle. The mechanism of attenuation, however, is largely unknown. Here, we used …

Continent-wide genomic analysis of the African buffalo (Syncerus caffer)

A Talenti, T Wilkinson, EA Cook, JD Hemmink… - Communications …, 2024 - nature.com
Abstract The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution
across much of sub-Saharan Africa. Genomic analysis can provide insights into the …

Profiling the immune epigenome across global cattle breeds

J Powell, A Talenti, A Fisch, JD Hemmink, E Paxton… - Genome Biology, 2023 - Springer
Background Understanding the variation between well and poorly adapted cattle breeds to
local environments and pathogens is essential for breeding cattle with improved climate and …

Genome-wide local ancestry and the functional consequences of admixture in African and European cattle populations

GP McHugo, JA Ward, SI Ng'ang'a, LAF Frantz… - Heredity, 2024 - nature.com
Bos taurus (taurine) and Bos indicus (indicine) cattle diverged at least 150,000 years ago
and, since that time, substantial genomic differences have evolved between the two …

Insights into trait-association of selection signatures and adaptive eQTL in indigenous African cattle

J Friedrich, S Liu, L Fang, J Prendergast, P Wiener - BMC genomics, 2024 - Springer
Background African cattle represent a unique resource of genetic diversity in response to
adaptation to numerous environmental challenges. Characterising the genetic landscape of …

Continent-wide genomic analysis of the African buffalo (Syncerus caffer)

A Talenti, T Wilkinson, EA Cook, JD Hemmink… - bioRxiv, 2023 - biorxiv.org
Abstract The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution
across much of sub-Saharan Africa. Genomic analysis can provide insights into the …