[HTML][HTML] Endoplasmic reticulum stress in melanoma pathogenesis and resistance

Y Kong, J Jiang, Y Huang, L Li, X Liu, Z Jin… - Biomedicine & …, 2022 - Elsevier
Melanoma is the most lethal skin cancer with rising incidence worldwide. Despite significant
advances in target therapy and immunotherapy, low response rates and the development of …

Regulation of endoplasmic reticulum stress-autophagy: a potential therapeutic target for ulcerative colitis

D Qiao, Z Zhang, Y Zhang, Q Chen, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic nonspecific inflammation that mainly affects the mucosa
and submucosa of the rectum and colon. Numerous studies have shown that endoplasmic …

FoxO signaling and mitochondria-related apoptosis pathways mediate tsinling lenok trout (Brachymystax lenok tsinlingensis) liver injury under high temperature stress

F Ma, L Zhao, R Ma, J Wang, L Du - International Journal of Biological …, 2023 - Elsevier
Tsinling lenok trout (Brachymystax lenok tsinlingensis) is a typical cold water fish. High
temperature has been shown to damage the liver of fish. However, few studies have …

How autophagy, a potential therapeutic target, regulates intestinal inflammation

SL Chen, CM Li, W Li, QS Liu, SY Hu, MY Zhao… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is a group of disorders that cause chronic inflammation in
the intestines, with the primary types including ulcerative colitis and Crohn's disease. The …

Ferroptosis is involved in Staphylococcus aureus-induced mastitis through autophagy activation by endoplasmic reticulum stress

L Bao, Y Zhao, S Duan, K Wu, R Shan, Y Liu… - International …, 2024 - Elsevier
Cell death caused by severe Staphylococcus aureus (S. aureus) infection is a fatal threat to
humans and animals. However, whether ferroptosis, an iron-dependent form of cell death, is …

Ouabain and chloroquine trigger senolysis of BRAF‐V600E‐induced senescent cells by targeting autophagy

V L'hôte, R Courbeyrette, G Pinna, J Cintrat… - Aging …, 2021 - Wiley Online Library
The expression of BRAF‐V600E triggers oncogene‐induced senescence in normal cells
and is implicated in the development of several cancers including melanoma. Here, we …

Unraveling the interplay between RAS/RAF/MEK/ERK signaling pathway and autophagy in cancer: From molecular mechanisms to targeted therapy

Y Huang, Y Zhen, Y Chen, S Sui, L Zhang - Biochemical Pharmacology, 2023 - Elsevier
Abstract RAS/RAF/MEK/ERK signaling pathway is one of the most important pathways of
Mitogen-activated protein kinases (MAPK), which widely participate in regulating cell …

Endoplasmic reticulum stress and tumor microenvironment in bladder cancer: the missing link

Z Nie, M Chen, X Wen, Y Gao, D Huang… - Frontiers in cell and …, 2021 - frontiersin.org
Bladder cancer is a common malignant tumor of the urinary system. Despite recent
advances in treatments such as local or systemic immunotherapy, chemotherapy, and …

A novel risk model based on autophagy-related LncRNAs predicts prognosis and indicates immune infiltration landscape of patients with cutaneous melanoma

Q Shu, Y Zhou, Z Zhu, X Chen, Q Fang, L Zhong… - Frontiers in …, 2022 - frontiersin.org
Cutaneous melanoma (CM) is a malignant tumor with a high incidence rate and poor
prognosis. Autophagy plays an essential role in the development of CM; however, the role of …

Histocompatibility Minor 13 (HM13), targeted by miR-760, exerts oncogenic role in breast cancer by suppressing autophagy and activating PI3K-AKT-mTOR pathway

H Yang, Z Li, Z Wang, X Zhang, X Dai, G Zhou… - Cell Death & …, 2022 - nature.com
Abstract Histocompatibility Minor 13 (HM13) is reported to participate in regulating multiple
cancers. In the present study, we uncovered that HM13 was highly expressed in breast …