Targeting tumor glycans for cancer therapy: successes, limitations, and perspectives

N Berois, A Pittini, E Osinaga - Cancers, 2022 - mdpi.com
Simple Summary Aberrant glycosylation is a common feature of many cancers, and it plays
crucial roles in tumor development and biology. Cancer progression can be regulated by …

[HTML][HTML] Recent advances and future perspectives on carbohydrate-based cancer vaccines and therapeutics

C Sorieul, F Papi, F Carboni, S Pecetta… - Pharmacology & …, 2022 - Elsevier
Carbohydrates are abundantly expressed on the surface of both eukaryotic and prokaryotic
cells, often as post translational modifications of proteins. Glycoproteins are recognized by …

NK cell-based immunotherapy in colorectal cancer

M Della Chiesa, C Setti, C Giordano, V Obino… - Vaccines, 2022 - mdpi.com
Human Natural Killer (NK) cells are all round players in immunity thanks to their powerful
and immediate response against transformed cells and the ability to modulate the …

CD44v6, STn & O-GD2: promising tumor associated antigens paving the way for new targeted cancer therapies

I Lodewijk, M Dueñas, JM Paramio… - Frontiers in …, 2023 - frontiersin.org
Targeted therapies are the state of the art in oncology today, and every year new Tumor-
associated antigens (TAAs) are developed for preclinical research and clinical trials, but few …

Anti-glycan monoclonal antibodies: Basic research and clinical applications

KM Gillmann, JS Temme, S Marglous, CE Brown… - Current opinion in …, 2023 - Elsevier
Anti-glycan monoclonal antibodies have important applications in human health and basic
research. Therapeutic antibodies that recognize cancer-or pathogen-associated glycans …

Nicotinamide-expanded allogeneic natural killer cells with CD38 deletion, expressing an enhanced CD38 chimeric antigen receptor, target multiple myeloma cells

A Edri, N Ben-Haim, A Hailu, N Brycman… - International Journal of …, 2023 - mdpi.com
Natural killer (NK) cells are a vital component of cancer immune surveillance. They provide
a rapid and potent immune response, including direct cytotoxicity and mobilization of the …

Carbohydrate‐Specific Monoclonal Antibody Therapeutics

M Lohman, H Rowe… - Carbohydrate‐Based …, 2023 - Wiley Online Library
Carbohydrates are a major class of biomolecules in living organisms that are necessary for
several important biological processes, such as cell–cell adhesion, cell signaling, protein …

[PDF][PDF] NK Cell-Based Immunotherapy in Colorectal Cancer. Vaccines 2022, 10, 1033

M Della Chiesa, C Setti, C Giordano, V Obino… - 2022 - academia.edu
Human Natural Killer (NK) cells are all round players in immunity thanks to their powerful
and immediate response against transformed cells and the ability to modulate the …