Ocular benzalkonium chloride exposure: problems and solutions

MH Goldstein, FQ Silva, N Blender, T Tran, S Vantipalli - Eye, 2022 - nature.com
Preservatives in multidose formulations of topical ophthalmic medications are crucial for
maintaining sterility but can be toxic to the ocular surface. Benzalkonium chloride (BAK) …

Detrimental effect of preservatives in eyedrops: implications for the treatment of glaucoma

C Baudouin - Acta ophthalmologica, 2008 - Wiley Online Library
Antiglaucoma medications are often associated with ocular adverse reactions such as dry
eye, and burning or stinging sensations. These undesirable effects may lead to treatment …

[HTML][HTML] Conjunctival proinflammatory and proapoptotic effects of latanoprost and preserved and unpreserved timolol: an ex vivo and in vitro study

PJ Pisella, C Debbasch, P Hamard… - … & visual science, 2004 - tvst.arvojournals.org
purpose. To compare the toxicity of latanoprost and preserved and unpreserved timolol on
conjunctival cells. Expression of inflammatory markers and MUC5AC-related mucin …

Dry eye syndrome-related quality of life in glaucoma patients

GCM Rossi, C Tinelli, GM Pasinetti… - European journal of …, 2009 - journals.sagepub.com
Purpose To verify the presence of dry eye syndrome (DES) in treated patients with glaucoma
and to analyze DES's impact on the patients' quality of life (QOL) versus the control group …

[HTML][HTML] Topical glaucoma medications–clinical implications for the ocular surface

F Fineide, N Lagali, MY Adil, R Arita, M Kolko, J Vehof… - The ocular …, 2022 - Elsevier
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to
reduce intraocular pressure remains the mainstay treatment. These eye drops frequently …

Fixed-combination intraocular pressure-lowering therapy for glaucoma and ocular hypertension: advantages in clinical practice

G Holló, F Topouzis, RD Fechtner - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: Several large, randomized, prospective clinical trials have demonstrated that
medical therapy to reduce intraocular pressure (IOP) delays the onset and decreases …

The tear ferning test: a simple clinical technique to evaluate the ocular tear film

AM Masmali, C Purslow, PJ Murphy - Clinical and Experimental …, 2014 - Taylor & Francis
A healthy tear film is very important for many major functions of the ocular surface. Dry eye
disease is a significant clinical problem that needs to be solved but the poor correlation …

Effect of chronic anti-glaucoma medications and trabeculectomy on tear osmolarity

SY Lee, TT Wong, J Chua, C Boo, YF Soh, L Tong - Eye, 2013 - nature.com
Purpose To evaluate the tear film osmolarity (TFO) and ocular surface clinical signs and
symptoms in chronically medicated glaucoma patients and post-trabeculectomy patients …

[HTML][HTML] Diagnostic tests based on pattern formation in drying body fluids–A mapping review

MO Kokornaczyk, NB Bodrova… - Colloids and Surfaces B …, 2021 - Elsevier
There are numerous diagnostic tests based on pattern formation in desiccating body fluids,
where the pattern or some of its characteristics constitute the diagnostic test outcome …

Brimonidine and timolol fixed-combination therapy versus monotherapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension

ER Craven, TR Walters, R Williams, C Chou… - Journal of Ocular …, 2005 - liebertpub.com
Purpose: The aim of this study was to compare the safety and intraocular pressure (IOP)-
lowering efficacy of a fixed combination of brimonidine 0.2% and timolol 0.5%(fixed …