Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Dietary protein for athletes: from requirements to optimum adaptation

SM Phillips, LJC Van Loon - Food, Nutrition and Sports …, 2013 - taylorfrancis.com
Opinion on the role of protein in promoting athletic performance is divided along the lines of
how much aerobic-based versus resistance-based activity the athlete undertakes. Athletes …

The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy

VC Foletta, LJ White, AE Larsen, B Léger… - … -European Journal of …, 2011 - Springer
Skeletal muscle atrophy occurs in many chronic diseases and disuse conditions. Its severity
reduces patient recovery, independence and quality of life. The discovery of two muscle …

Sedentary behavior and the biological hallmarks of aging

J Raffin, P de Souto Barreto, AP Le Traon… - Ageing Research …, 2023 - Elsevier
While the benefits of physical exercise for a healthy aging are well-recognized, a growing
body of evidence shows that sedentary behavior has deleterious health effects …

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?

T Van Wessel, A De Haan, WJ Van Der Laarse… - European journal of …, 2010 - Springer
An inverse relationship exists between striated muscle fiber size and its oxidative capacity.
This relationship implies that muscle fibers, which are triggered to simultaneously increase …

Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

GB Kubat, E Bouhamida, O Ulger, I Turkel, G Pedriali… - Mitochondrion, 2023 - Elsevier
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Molecular mechanism of sarcopenia and cachexia: recent research advances

K Sakuma, W Aoi, A Yamaguchi - Pflügers Archiv-European Journal of …, 2017 - Springer
Skeletal muscle provides a fundamental basis for human function, enabling locomotion and
respiration. Muscle loss occurs as a consequence of several chronic diseases (cachexia) …

Sarcopenic obesity: molecular clues to a better understanding of its pathogenesis?

R Kob, LC Bollheimer, T Bertsch, C Fellner, M Djukic… - Biogerontology, 2015 - Springer
An age-dependent decline in skeletal muscle mass, strength, and endurance during the
aging process is a physiological development, but several factors may exacerbate this …

Current understanding of sarcopenia: possible candidates modulating muscle mass

K Sakuma, W Aoi, A Yamaguchi - Pflügers Archiv-European Journal of …, 2015 - Springer
The world's elderly population is expanding rapidly, and we are now faced with the
significant challenge of maintaining or improving physical activity, independence, and …

Characterization and regulation of mechanical loading‐induced compensatory muscle hypertrophy

GR Adams, MM Bamman - Comprehensive Physiology, 2012 - Wiley Online Library
In mammalian systems, skeletal muscle exists in a dynamic state that monitors and regulates
the physiological investment in muscle size to meet the current level of functional demand …