West Nile virus (WNV)(Flavivirus: Flaviviridae) is the most widespread arbovirus in the world.
A significant range expansion occurred beginning in 1999 when the virus was introduced …

Since the emergence of West Nile virus (WNV) in North America in 1999, understanding of
the clinical features, spectrum of illness and eventual functional outcomes of human illness …

Japanese encephalitis is an acute zoonotic, mosquito-borne disease caused by Japanese
encephalitis virus (JEV). Japanese encephalitis is characterized by extensive inflammation …

Antibody binding to the icosahedral arrangement of envelope proteins on the surface of
flaviviruses can result in neutralization or enhancement of infection. We evaluated how …

Monoclonal antibodies (mAbs) have long provided powerful research tools for virologists to
understand the mechanisms of virus entry into host cells and of antiviral immunity. Even so …

Dengue viruses (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV) are
major global health and growing medical problems. While a live-attenuated vaccine exists …

Previous studies have demonstrated that monoclonal antibodies (MAbs) against an epitope
on the lateral surface of domain III (DIII) of the West Nile virus (WNV) envelope (E) strongly …

The resurgence of West Nile virus (WNV) in North America and Europe in recent years has
raised the concerns of local authorities and highlighted that mosquito-borne disease is not …

Antibody protection against flaviviruses is associated with the development of neutralizing
antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) …

Flaviviruses are a group of~ 70 small RNA viruses responsible for significant morbidity and
mortality across the globe. Efforts to develop effective vaccines for several clinically …