The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) have pleiotropic
effects in multiple organs including brain, heart, and skeletal muscle by serving as an …

Ketone bodies are small compounds derived from fatty acids that behave as an alternative
mitochondrial energy source when insulin levels are low, such as during fasting or …

Septic cardiomyopathy is a life‐threatening complication of severe sepsis and septic shock.
Oxidative stress and mitochondrial dysfunction have been identified as significant …

Ketone bodies are crucial intermediate metabolites widely associated with treating
metabolic diseases. Accumulating evidence suggests that ketone bodies may act as …

Microglial activation is a key event in neuroinflammation, which, in turn, is a central process
in neurological disorders. In this study, we investigated the protective effects of D-beta …

Abstract Background Ketone bodies (KBs) are an alternative energy supply for brain
functions when glucose is limited. The most abundant ketone metabolite, 3-β …

Abstract In septic mice, 3-hydroxybutyrate-sodium-salt has shown to partially prevent sepsis-
induced muscle weakness. Although effective, the excessive sodium load was toxic. We …

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally
lethal prognosis despite maximal standard therapies. Here, we present a consensus …

Ulcerative colitis (UC) is an inflammatory condition that affects the colon's lining and
increases the risk of colon cancer. Despite ongoing research, there is no identified cure for …

Ketone bodies, or ketones, are an alternative energy source and have several nonmetabolic
signaling actions, such as inhibiting inflammation. Because of this, exogenous ketone …