Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

Background Closed loop deep brain stimulation (clDBS) in Parkinson's disease (PD) using
subthalamic (STN) neural feedback has been shown to be efficacious only in the acute post …

Introduction: Several software and hardware advances in the field of deep brain stimulation
(DBS) have been realized in recent years and devices from three manufacturers are …

Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …

Advancing conventional open‐loop DBS as a therapy for PD is crucial for overcoming
important issues such as the delicate balance between beneficial and adverse effects and …

Rapid advancements in neurostimulation technologies are providing relief to an
unprecedented number of patients affected by debilitating neurologic and psychiatric …

Deep brain stimulation (DBS) surgery offers a unique opportunity to record local field
potentials (LFPs), the electrophysiological population activity of neurons surrounding the …

Freezing of gait (FOG) is a devastating axial motor symptom in Parkinson's disease (PD)
leading to falls, institutionalization, and even death. The response of FOG to dopaminergic …

Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …