Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …

Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …

Background The mammalian retina contains an autonomous circadian clock that controls
various aspects of retinal physiology and function, including dopamine (DA) release by …

Genetically complex ocular neuropathies, such as glaucoma, are a major cause of visual
impairment worldwide. There is a growing need to generate suitable human representative …

Circadian clocks in the mammalian retina regulate a diverse range of retinal functions that
allow the retina to adapt to the light-dark cycle. Emerging evidence suggests a link between …

Circadian clocks are cell-autonomous, molecular pacemakers regulating a wide variety of
behavioural and physiological processes in accordance with the 24​ h light/dark cycle. The …

Surgical removal of the thyroid gland (TG) for treating thyroid disorders leaves the patients
on lifelong hormone replacement that partially compensates the physiological needs, but …

The retinal circadian system consists of a network of clocks located virtually in every retinal
cell-type. Although it is established that the circadian clock regulates many rhythmic …

Purpose To explore whether circadian clock genes contribute to elicit inflammation in
experimental dry eye (EDE). Methods RNA sequencing analyzed mRNA expression …

The mammalian central nervous system (CNS) is incapable of regenerating damaged
axons; as a result, trauma or neurodegenerative diseases such as glaucoma cause a …