Solution-phase hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) is
a widespread tool for structural analysis across academia and the biopharmaceutical …

Introduction: Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful
methodology to study protein dynamics, protein folding, protein-protein interactions, and …

The folding/misfolding and pharmacological rescue of multidomain ATP-binding cassette
(ABC) C-subfamily transporters, essential for organismal health, remain incompletely …

Nucleosomes, the basic structural units of chromatin, hinder recruitment and activity of
various DNA repair proteins, necessitating modifications that enhance DNA accessibility …

The last∼ 25 years has seen mass spectrometry (MS) emerge as an integral method in the
structural biology toolkit. In particular, MS has enabled the structural characterization of …

African Trypanosomes have developed elaborate mechanisms to escape the adaptive
immune response, but little is known about complement evasion particularly at the early …

Celiac disease is triggered by partially digested gluten proteins. Enzyme therapies that
complete protein digestion in vivo could support a gluten-free diet, but the barrier to …

Plants belonging to the genus Nepenthes are carnivorous, using specialized pitfall traps
called “pitchers” that attract, capture, and digest insects as a primary source of nutrients. We …

Biological processes are the result of noncovalent, protein–ligand interactions, where the
ligands range from small organic and inorganic molecules to lipids, nucleic acids, peptides …

Background Carnivorous plants have been fascinating researchers with their unique
characters and bioinspired applications. These include medicinal trait of some carnivorous …