The term monoclonal gammopathy of renal significance (MGRS) was introduced by the
International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …

Summary This International Myeloma Working Group consensus updates the disease
definition of multiple myeloma to include validated biomarkers in addition to existing …

Onconephrology is a new subspecialty of nephrology that recognizes the important
intersections of kidney disease with cancer. This intersection takes many forms and includes …

Monoclonal gammopathy is a common condition, particularly in the elderly. It can indicate
symptomatic multiple myeloma or another overt malignant lymphoid disorder requiring …

Monoclonal gammopathy of renal significance (MGRS) regroups all renal disorders caused
by a monoclonal immunoglobulin (MIg) secreted by a nonmalignant B-cell clone. By …

The kidney is involved in 70% of patients with immunoglobulin light-chain (AL) amyloidosis,
but little is known on progression or reversibility of renal involvement, and criteria for renal …

The immune system and the kidneys are closely linked. In health the kidneys contribute to
immune homeostasis, while components of the immune system mediate many acute forms …

Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a
large prospective population-based cohort, we aimed to establish a reference interval for …

Light chain (AL) amyloidosis is caused by a usually small plasma cell clone producing a
misfolded light chain that deposits in tissues. Survival is mostly determined by the severity of …

Monoclonal Gammopathy of Renal Significance Monoclonal gammopathy of renal
significance is a B-cell or plasma-cell clonal disorder that does not meet the criteria for …