[HTML][HTML] Oral antiviral treatments for COVID-19: opportunities and challenges

L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
The use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication
and prevent disease progression to a more severe form. However, the timing of antiviral …

[HTML][HTML] Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants

WR Strohl, Z Ku, Z An, SF Carroll, BA Keyt, LM Strohl - BioDrugs, 2022 - Springer
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …

[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

[HTML][HTML] The association of airborne particulate matter and benzo [a] pyrene with the clinical course of COVID-19 in patients hospitalized in Poland

P Rzymski, B Poniedziałek, J Rosińska… - Environmental …, 2022 - Elsevier
Air pollution can adversely affect the immune response and increase the severity of the viral
disease. The present study aimed to explore the relationship between symptomatology …

[PDF][PDF] Management of SARS-CoV-2 infection: Recommendations of the Polish Association of Epidemiologists and Infectiologists as of April 26, 2021

R Flisiak, A Horban, J Jaroszewicz… - Pol Arch Intern …, 2021 - ppm.gumed.edu.pl
Pathogenesis SARS-CoV-2 spreads through respiratory droplet transmission as well as
contaminated objects or surfaces and enters host cells via the functional cell receptor ACE2 …

[HTML][HTML] Demographic and clinical overview of hospitalized COVID-19 patients during the first 17 months of the pandemic in Poland

R Flisiak, P Rzymski, D Zarębska-Michaluk… - Journal of Clinical …, 2021 - mdpi.com
Long-term analyses of demographical and clinical characteristics of COVID-19 patients can
provide a better overview of the clinical course of the disease. They can also help …

Prognostic parameters of in‐hospital mortality in COVID‐19 patients—An Italian experience

M Ruscica, C Macchi, S Iodice… - European journal of …, 2021 - Wiley Online Library
Abstract Background During COVID‐19 outbreak, Italy was the first country in Europe to be
heavily affected with an intensive care unit mortality of 26%. In order to reduce this …

Circulating biomarkers of inflammaging as potential predictors of COVID-19 severe outcomes

J Sabbatinelli, G Matacchione, A Giuliani… - Mechanisms of Ageing …, 2022 - Elsevier
The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …

Alterations in platelets during SARS-CoV-2 infection

M Brambilla, P Canzano, A Becchetti, E Tremoli… - Platelets, 2022 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic syndrome caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. SARS-CoV-2 infection …

Effectiveness of tocilizumab with and without dexamethasone in patients with severe COVID-19: a retrospective study

D Zarębska-Michaluk, J Jaroszewicz… - Journal of …, 2021 - Taylor & Francis
Purpose The pathogenesis of coronavirus disease 2019 (COVID-19) is complicated, and in
addition to antiviral therapy and combating coagulopathy, treatment should also include …