Redox regulation by protein S-glutathionylation: from molecular mechanisms to implications in health and disease

A Musaogullari, YC Chai - International journal of molecular sciences, 2020 - mdpi.com
S-glutathionylation, the post-translational modification forming mixed disulfides between
protein reactive thiols and glutathione, regulates redox-based signaling events in the cell …

Chlorogenic acid induces apoptosis and cell-cycle arrest in colorectal cancer cells

AG Ranjbary, A Bagherzadeh, SS Sabbaghi… - Molecular Biology …, 2023 - Springer
Background Apoptotic agents from natural products like phenolic compounds can be used
effectively in the treatment of cancer. Chlorogenic acid (CGA) is one of the phenolic …

Colorimetric detection of extracellular hydrogen peroxide using an integrated microfluidic device

E Dervisevic, NH Voelcker, G Risbridger… - Analytical …, 2022 - ACS Publications
It is well known that hydrogen peroxide (H2O2) is a signaling molecule essential for vital
physiological reactions in mammalian cells, such as cell survival, intercellular …

Investigation of natural compounds for therapeutic potential in streptozotocin-induced diabetic neuroinflammation and neuropathic pain

M Faheem, A Khan, FA Shah, S Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Diabetic neuropathy (DN) is a serious microvascular complication of diabetes mellitus (DM)
that impacts the nervous system. Several risk factors are involved in the progression and …

Sinapic acid reduces ischemia/reperfusion injury due to testicular torsion/detorsion in rats

V Unsal, E Kolukcu, F Gevrek, F Firat - Andrologia, 2021 - Wiley Online Library
This study aimed to investigate the protective effect of sinapic acid (SA) on biochemical and
histopathological changes in an experimental testicular torsion‐detorsion rat model. Twenty …

[HTML][HTML] Oxazine drug-seed induces paraptosis and apoptosis through reactive oxygen species/JNK pathway in human breast cancer cells

NY Kim, D Dukanya, G Sethi, SS Girimanchanaika… - Translational …, 2024 - Elsevier
Small molecule-driven JNK activation has been found to induce apoptosis and paraptosis in
cancer cells. Herein pharmacological effects of synthetic oxazine (4aS, 7aS)-3-((4-(4‑chloro …

Phenethyl Isothiocyanate-Conjugated Chitosan Oligosaccharide Nanophotosensitizers for Photodynamic Treatment of Human Cancer Cells

I Bae, TG Kim, T Kim, D Kim, DH Kim, J Jo… - International Journal of …, 2022 - mdpi.com
The aim of this study is to synthesize phenethyl-conjugated chitosan oligosaccharide
(COS)(abbreviated as ChitoPEITC) conjugates and then fabricate chlorin E6 (Ce6) …

Uncovering Metabolic Alterations in HCT-116 Colon Cancer Cells upon Exposure to Bamboo Leaf Extract Obtained from Guadua incana Londoño

LC Chitiva, MA Santamaría-Torres… - Molecules, 2024 - mdpi.com
Metabolic alterations are increasingly recognized as important aspects of colorectal cancer
(CRC), offering potential avenues for identifying therapeutic targets. Previous studies have …

Oral administration of cysteine peptides attenuates UV-B-induced skin erythema and pigmentation in humans

A Sakuma, Y Kai, Y Yamasaki, T Tanaka, T Sakurai - Scientific Reports, 2024 - nature.com
The oral administration of antioxidants may suppress UV-B-induced skin damage. HITHION
YH-15, the extract of Torula yeast (Cyberlindnera jadinii), is rich in cysteine-containing …

The type-1 ribosome-inactivating protein OsRIP1 triggers caspase-independent apoptotic-like death in HeLa cells

S Chen, CF Lóssio, I Verbeke, J Verduijn… - Food and Chemical …, 2021 - Elsevier
Ribosome-inactivating proteins (RIPs) are capable of removing a specific adenine from 28S
ribosomal RNA, thus inhibiting protein biosynthesis in an irreversible manner. In this study …