The gut–brain axis and the microbiome: mechanisms and clinical implications

V Osadchiy, CR Martin, EA Mayer - Clinical Gastroenterology and …, 2019 - Elsevier
Background & Aims Based largely on results from preclinical studies, the concept of a brain
gut microbiome axis has been established, mediating bidirectional communication between …

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

GB Rogers, DJ Keating, RL Young, ML Wong… - Molecular …, 2016 - nature.com
The human body hosts an enormous abundance and diversity of microbes, which perform a
range of essential and beneficial functions. Our appreciation of the importance of these …

The infant microbiome development: mom matters

NT Mueller, E Bakacs, J Combellick, Z Grigoryan… - Trends in molecular …, 2015 - cell.com
The infant microbiome plays an essential role in human health and its assembly is
determined by maternal–offspring exchanges of microbiota. This process is affected by …

Gut microbiota, obesity and diabetes

E Patterson, PM Ryan, JF Cryan… - Postgraduate …, 2016 - academic.oup.com
The central role of the intestinal microbiota in the progression and, equally, prevention of
metabolic dysfunction is becoming abundantly apparent. The symbiotic relationship …

Microbiota and neurodevelopmental windows: implications for brain disorders

YE Borre, GW O'Keeffe, G Clarke, C Stanton… - Trends in molecular …, 2014 - cell.com
Gut microbiota is essential to human health, playing a major role in the bidirectional
communication between the gastrointestinal tract and the central nervous system. The …

The prenatal gut microbiome: are we colonized with bacteria in utero?

RW Walker, JC Clemente, I Peter, RJF Loos - Pediatric obesity, 2017 - Wiley Online Library
The colonization of the gut with microbes in early life is critical to the developing newborn
immune system, metabolic function and potentially future health. Maternal microbes are …

Connections between the gut microbiome and metabolic hormones in early pregnancy in overweight and obese women

LF Gomez-Arango, HL Barrett, HD McIntyre… - Diabetes, 2016 - Am Diabetes Assoc
Overweight and obese women are at a higher risk for gestational diabetes mellitus. The gut
microbiome could modulate metabolic health and may affect insulin resistance and lipid …

[HTML][HTML] Development and physiology of the rumen and the lower gut: Targets for improving gut health

MA Steele, GB Penner, F Chaucheyras-Durand - Journal of dairy science, 2016 - Elsevier
The gastrointestinal epithelium of the dairy cow and calf faces the challenge of protecting the
host from the contents of the luminal milieu while controlling the absorption and metabolism …

Systematic review of the human milk microbiota

JL Fitzstevens, KC Smith, JI Hagadorn… - Nutrition in Clinical …, 2017 - Wiley Online Library
Human milk–associated microbes are among the first to colonize the infant gut and may help
to shape both short‐and long‐term infant health outcomes. We performed a systematic …

Food for thought: The role of nutrition in the microbiota-gut–brain axis

CS Oriach, RC Robertson, C Stanton, JF Cryan… - Clinical Nutrition …, 2016 - Elsevier
Recent research has provided strong evidence for the role of the commensal gut microbiota
in brain function and behaviour. Many potential pathways are involved in this bidirectional …