Abuse potential and toxicity of the synthetic cathinones (ie,“Bath salts”)

AL Riley, KH Nelson, P To, R López-Arnau, P Xu… - Neuroscience & …, 2020 - Elsevier
The synthetic cathinones are derived from the naturally occurring drug cathinone found in
the khat plant (Catha edulis) and have chemical structures and neurochemical …

Sex as a biological variable: Drug use and abuse

AL Riley, BJ Hempel, MM Clasen - Physiology & behavior, 2018 - Elsevier
The study of sex as a biological variable is a necessary emphasis across a wide array of
endpoints, including basic neuroscience, medicine, mental health, physiology and behavior …

Impact of the aversive effects of drugs on their use and abuse

AL Riley, HN Manke, S Huang - Behavioural Neurology, 2022 - Wiley Online Library
Drug use and abuse are complex issues in that the basis of each may involve different
determinants and consequences, and the transition from one to the other may be equally …

The synthetic cathinone α-pyrrolidinovalerophenone (α-PVP): pharmacokinetic and pharmacodynamic clinical and forensic aspects

L Nóbrega, RJ Dinis-Oliveira - Drug metabolism reviews, 2018 - Taylor & Francis
New psychoactive substances (NPS), often referred as 'legal highs' or 'designer drugs', are
derivatives and analogs of existing psychoactive drugs that are introduced in the …

[HTML][HTML] Effects of α-pyrrolidino-phenone cathinone stimulants on locomotor behavior in female rats

MA Taffe, JD Nguyen, SA Vandewater, Y Grant… - Drug and alcohol …, 2021 - Elsevier
The α-pyrrolidino-phenone cathinone stimulants first came to widespread attention because
of bizarre behavior consequent to the use of α-pyrrolidinopentiophenone (α-PVP,“flakka”) …

Hippocampal-dependent inhibitory learning and memory processes in the control of eating and drug taking

MM Clasen, AL Riley… - Current Pharmaceutical …, 2020 - benthamdirect.com
As manifestations of excessive and uncontrolled intake, obesity and drug addiction have
generated much research aimed at identifying common neuroadaptations that could …

Stereoselective neurochemical, behavioral, and cardiovascular effects of α‐pyrrolidinovalerophenone enantiomers in male rats

CW Schindler, EB Thorndike, HM Walters… - Addiction …, 2020 - Wiley Online Library
The synthetic cathinone α‐pyrrolidinovalerophenone (α‐PVP) continues to be abused
despite being banned by regulatory agencies. The abused formulation of α‐PVP is a …

Sex differences in α-pyrrolidinopentiophenone (α-PVP)-induced taste avoidance, place preference, hyperthermia and locomotor activity in rats

KH Nelson, HN Manke, A Imanalieva, KC Rice… - Pharmacology …, 2019 - Elsevier
Rationale The majority of synthetic cathinone research has used only male subjects, and as
a result there are few studies assessing the impact of biological sex on their effects …

Conditioned taste avoidance and conditioned place preference induced by the third-generation synthetic cathinone eutylone in female sprague-dawley rats.

RA Jones, S Huang, HN Manke… - Experimental and Clinical …, 2023 - psycnet.apa.org
Recently, use of the synthetic cathinone (aka “bath salt”) eutylone has risen in the United
States and globally. Due to its novelty in drug markets, its affective properties remain largely …

Assessment of aversive effects of methylone in male and female Sprague-Dawley rats: Conditioned taste avoidance, body temperature and activity/stereotypies

HN Manke, KH Nelson, A Vlachos, JM Bailey… - Neurotoxicology and …, 2021 - Elsevier
Methylone's rewarding effects have been well characterized; however, little is known about
its aversive effects and how such effects may be impacted by sex. In this context, the present …