Human coronavirus (HCoV) infection causes respiratory diseases with mild to severe
outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly …

Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism
that culminates with the lysosomal degradation of superfluous or potentially dangerous …

Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …

Coronaviruses are pathogens with a serious impact on human and animal health. They
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …

Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …

Positive single-strand RNA (+ RNA) viruses can remodel host cell membranes to induce a
replication organelle (RO) isolating the replication of their genome from innate immunity …

Autophagy is a cellular process that targets proteins, lipids and organelles to lysosomes for
degradation, but it has also been shown to combat infection with various pathogenic …

Positive-sense RNA viruses hijack intracellular membranes that provide niches for viral RNA
synthesis and a platform for interactions with host proteins. However, little is known about …

Autophagy is a cellular response to starvation that generates autophagosomes to carry long-
lived proteins and cellular organelles to lysosomes for degradation. Activation of autophagy …

Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …