Circulating miRNA analysis for cancer diagnostics and therapy

L Valihrach, P Androvic, M Kubista - Molecular Aspects of Medicine, 2020 - Elsevier
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …

[HTML][HTML] Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics

E Geeurickx, A Hendrix - Molecular aspects of medicine, 2020 - Elsevier
Assessment of cell free DNA (cfDNA) and RNA (cfRNA), circulating tumor cells (CTC) and
extracellular vesicles (EV) in blood or other bodily fluids can enable early cancer detection …

Current challenges and best practices for cell-free long RNA biomarker discovery

L Cabús, J Lagarde, J Curado, E Lizano… - Biomarker …, 2022 - Springer
The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …

Considerations and suggestions for the reliable analysis of miRNA in plasma using qRT-PCR

E Ban, EJ Song - Genes, 2022 - mdpi.com
MicroRNAs (miRNAs) are promising molecules that can regulate gene expression, and their
expression level and type have been associated with early diagnosis, targeted therapy, and …

The role of miR-21 in osteoblasts–osteoclasts coupling in vitro

A Smieszek, K Marcinkowska, A Pielok, M Sikora… - Cells, 2020 - mdpi.com
MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …

Circulating microRNAs as reliable tumor biomarkers: Opportunities and Challenges facing Clinical Application

SM El-Daly, SA Gouhar, ZY Abd Elmageed - Journal of Pharmacology and …, 2023 - ASPET
MicroRNAs (miRNAs) are involved in the development of human malignancies, and cells
have the ability to secrete these molecules into extracellular compartments. Thus, cell-free …

LiKidMiRs: A ddPCR-based panel of 4 circulating miRNAs for detection of renal cell carcinoma

JP Sequeira, V Constâncio, S Salta, J Lobo… - Cancers, 2022 - mdpi.com
Simple Summary Early detection of renal cell carcinoma (RCC) significantly increases the
likelihood of curative treatment, avoiding the need of adjuvant therapies, associated side …

Circulating exosomal miRNAs as novel biomarkers perform superior diagnostic efficiency compared with plasma miRNAs for large-artery atherosclerosis stroke

M Niu, H Li, X Li, X Yan, A Ma, X Pan… - Frontiers in …, 2021 - frontiersin.org
Recently, exosomal miRNAs have been reported to be associated with some diseases, and
these miRNAs can be used for diagnosis and treatment. However, diagnostic biomarkers of …

[HTML][HTML] Integrating circulating miRNA analysis in the clinical management of lung cancer: Present or future?

R Lampignano, V Kloten, T Krahn… - Molecular Aspects of …, 2020 - Elsevier
Liquid biopsy holds great promise to complement traditional analysis on cancerous tissue
during clinical management of cancer: screening of patients,(early) disease diagnosis …

Obesity affects the proliferative potential of equine endometrial progenitor cells and modulates their molecular phenotype associated with mitochondrial metabolism

A Smieszek, K Marcinkowska, A Pielok, M Sikora… - Cells, 2022 - mdpi.com
The study aimed to investigate the influence of obesity on cellular features of equine
endometrial progenitor cells (Eca EPCs), including viability, proliferation capacity …