Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Recent advances on reactive oxygen species-responsive delivery and diagnosis system

H Ye, Y Zhou, X Liu, Y Chen, S Duan, R Zhu… - …, 2019 - ACS Publications
Reactive oxygen species (ROS) play crucial roles in biological metabolism and intercellular
signaling. However, ROS level is dramatically elevated due to abnormal metabolism during …

Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: An update

RR Castillo, D Lozano, B González… - Expert opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction Mesoporous silica nanoparticles (MSNs) are outstanding
nanoplatforms for drug delivery. Herein, the most recent advances to turn MSN-based …

Clickable polysaccharides for biomedical applications: a comprehensive review

MK Yazdi, SM Sajadi, F Seidi, N Rabiee… - Progress in polymer …, 2022 - Elsevier
Recent advances in materials science and engineering highlight the importance of
designing sophisticated biomaterials with well-defined architectures and tunable properties …

[HTML][HTML] Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in peri-implant space and bone formation in …

M Chen, Y Sun, Y Hou, Z Luo, M Li, Y Wei, M Chen… - Bioactive materials, 2022 - Elsevier
To solve the issue of unsatisfactory recruitment of mesenchymal stem cells (MSCs) around
implant in osteoporotic fractures, we fabricated a ROS-responsive system on titanium …

An Antisense Oligonucleotide-Loaded Blood–Brain Barrier Penetrable Nanoparticle Mediating Recruitment of Endogenous Neural Stem Cells for the Treatment of …

Y Sun, J Kong, X Ge, M Mao, H Yu, Y Wang - ACS nano, 2023 - ACS Publications
Parkinson's disease (PD) is a neurodegenerative disease characterized by the death of
dopaminergic (DA) neurons and currently cannot be cured. One selected antisense …

Free‐blockage mesoporous silica nanoparticles loaded with cerium oxide as ROS‐responsive and ROS‐scavenging nanomedicine

O Purikova, I Tkachenko, B Šmíd… - Advanced Functional …, 2022 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) with reactive oxygen species (ROS)‐responsive
“nanogate” as drug delivery platforms are extensively investigated for biomedical …

Size switchable nanoclusters fueled by extracellular ATP for promoting deep penetration and MRI‐guided tumor photothermal therapy

Z Zhou, Y Liu, M Zhang, C Li, R Yang… - Advanced Functional …, 2019 - Wiley Online Library
Protein‐based theranostic agents (PBTAs) exhibit superior performance in the diagnosis
and therapy of cancers. However, the in vivo applications of PBTA are largely limited by …

Click chemistry selectively activates an auristatin protodrug with either intratumoral or systemic tumor-targeting agents

JM McFarland, M Alečković, G Coricor… - ACS Central …, 2023 - ACS Publications
The Click Activated Protodrugs Against Cancer (CAPAC) platform enables the activation of
powerful cancer drugs at tumors. CAPAC utilizes a click chemistry reaction between …