Artemisinin, a novel antimalarial drug: biochemical and molecular approaches for enhanced production

MZ Abdin, M Israr, RU Rehman, SK Jain - Planta medica, 2003 - thieme-connect.com
Artemisinin, a sesquiterpene lactone containing an endoperoxide bridge, has been isolated
from the aerial parts of Artemisia annua L. plants. It is effective against both drug-resistant …

Artemisinin: current state and perspectives for biotechnological production of an antimalarial drug

C Liu, Y Zhao, Y Wang - Applied microbiology and biotechnology, 2006 - Springer
Artemisinin isolated from the aerial parts of Artemisia annua L. is a promising and potent
antimalarial drug which has a remarkable activity against chloroquine-resistant and …

AaMYB1 and its orthologue AtMYB61 affect terpene metabolism and trichome development in Artemisia annua and Arabidopsis thaliana

L Matías‐Hernández, W Jiang, K Yang… - The Plant …, 2017 - Wiley Online Library
The effective anti‐malarial drug artemisinin (AN) isolated from Artemisia annua is relatively
expensive due to the low AN content in the plant as AN is only synthesized within the …

Expression of a chimeric farnesyl diphosphate synthase gene in Artemisia annua L. transgenic plants via Agrobacterium tumefaciens-mediated transformation

DH Chen, HC Ye, GF Li - Plant Science, 2000 - Elsevier
An Agrobacterium tumefaciens-mediated transformation system was developed for
Artemisia annua L. Using this system a cDNA encoding farnesyl diphosphate synthase (FDS …

[图书][B] Functions of plant secondary metabolites and their exploitation in biotechnology

M Wink - 1999 - books.google.com
Annual Plant Reviews, Volume 3 The structure of this volume is slanted towards plant
protection, with authors offering new insights into the functions of plant secondary …

Effect of light irradiation on hairy root growth and artemisinin biosynthesis of Artemisia annua L

C Liu, C Guo, Y Wang, F Ouyang - Process Biochemistry, 2002 - Elsevier
The effects of light irradiation on growth and production of artermisinin were studied in hairy
root cultures of Artemisia annua L. When the hairy roots were cultured under illumination at …

Improvement of artemisinin production by chitosan in hairy root cultures of Artemisia annua L.

W Putalun, W Luealon, W De-Eknamkul, H Tanaka… - Biotechnology …, 2007 - Springer
Artemisinin production by hairy roots of Artemisia annua L. was increased 6-fold to 1.8 μg
mg− 1 dry wt over 6 days by adding 150 mg chitosan l− 1. The increase was dose …

Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua

A Baldi, VK Dixit - Bioresource technology, 2008 - Elsevier
Artemisinin, isolated from the shrub-Artemisia annua, is a sesquiterpene lactone used to
treat multi-drug resistant strains of falciparum malaria. It is also effective against a wide …

Phenolic Content in Differentiated Tissue Cultures of Untransformed and Agrobacterium-Transformed Roots of Anise (Pimpinella anisum L.)

N Andarwulan, K Shetty - Journal of agricultural and food …, 1999 - ACS Publications
To investigate the role of differentiation of anise tissue cultures on total phenolic and
anethole contents, benzylaminopurine-and thidiazuron-induced shoot cultures were …

Phytohormones jasmonic acid, salicylic acid, gibberellins, and abscisic acid are key mediators of plant secondary metabolites

ZY Lv, WJ Sun, R Jiang, JF Chen, X Ying… - World Journal of …, 2021 - journals.lww.com
Until recently, many studies on the role of phytohormones in plant secondary metabolism
focused on jasmonic acid (JA), salicylic acid (SA), gibberellins (GA), and abscisic acid …